Many universities now offer a course in biomedical optics, but lack a textbook specifically addressing the topic. Intended to fill this gap, An Introduction to Biomedical Optics is the first comprehensive, introductory text describing both diagnostic and therapeutic optical methods in medicine. It provides the fundamental background needed for graduate students in biomedical and electrical engineering, physics, biology, and medicine to learn about several biomedical optics issues.
The textbook is divided into three main sections: general optics theory, therapeutic applications of light, and diagnostic optical methods. Each chapter has different levels of detail to build students' knowledge from one level to the next. The first section covers the history of optics theory and the basic science behind light-tissue interactions. It also introduces the relevant approaches and approximations used to describe light propagation in turbid biological media. In the second section, the authors look more closely at light-tissue interactions and their applications in different medical areas, such as wound healing and tissue welding. The final section examines the various diagnostic methods that are employed using optical techniques. Throughout the text, the authors employ numerical examples of clinical and research requirements.
Fulfilling the need for a concise biomedical optics textbook, An Introduction to Biomedical Optics addresses the theory and applications of this growing field.
Introduction to the Use of Light for Diagnostic and Therapeutic Modalities
What Is Biomedical Optics?
Biomedical Optics Timeline
Elementary Optical Discoveries
Historical Events in Therapeutic and Diagnostic Use of Light
Light Sources
Current State of the Art
Summary
Additional Reading
Problems
Review of Optical Principles: Fundamental Electromagnetic Theory and Description of Light Sources
Definitions in Optics
Kirchhoff's Laws of Radiation
Electromagnetic Wave Theory
Light Sources
Applications of Various Lasers
Summary
Additional Reading
Problems
Review of Optical Principles: Classical Optics
Geometrical Optics
Other Optical Principles
Quantum Physics
Gaussian Optics
Summary
Additional Reading
Problems
Review of Optical Interaction Properties
Absorption and Scattering
Summary
Additional Reading
Problems
Light-Tissue Interaction Variables
Laser Variables
Tissue Variables
Light Transportation Theory
Light Propagation under Dominant Absorption
Summary
Nomenclature
Additional Reading
Problems
Light-Tissue Interaction Theory
Approximations of the Equation of Radiative Transport
Summary
Additional Reading
Problems
Numerical and Deterministic Methods in Light-Tissue Interaction Theory
Numerical Method to Solve the Equation of Radiative Transport
Measurement of Optical Parameters
Temperature Effects of Light-Tissue Interaction
Summary
Additional Reading
Problems
Light-Tissue Interaction Mechanisms and Applications: Photophysical
Range of Photophysical Mechanisms
Photoablation
Photoacoustics
Birefringence Effects
Polarization Effects
Optical Activity
Evanescent Wave Interaction in Biomedical Optics
Phase Interference Effects
Spectroscopy
Endoscopy
Summary
Additional Reading
Problems
Light-Tissue Interaction Mechanisms and Applications: Photochemical
Basic Photochemical Principles
Photochemical Effects
Summary
Additional Reading
Problems
Light-Tissue Interaction Mechanisms and Applications: Photobiological
Photobiological Biostimulation
Photobiological Effects
Excitation of Chromophores
Optic Nerve-Cell Depolarization under the Influence of Light (Vision)
Summary
Additional Reading
Problems
THERAPEUTIC APPLICATIONS OF LIGHT
Therapeutic Applications of Light: Photophysical
Delivery Considerations
Pulsed Laser Use in Cardiology
Dentistry and Oral Surgery
Ophthalmology
Optical Tweezers
Summary
Additional Reading
Problems
Therapeutic Applications of Light: Photochemical
Vascular Welding
Cosmetic Surgery
Oncology
Summary
Additional Reading
Problems
Therapeutic Applications of Light: Photobiological
Cardiology & Cardiovascular Surgery
Soft tissue Treatment
Dermatology
Fetal Surgery
Gastroenterology
General Surgery
Gynecology
Neurosurgery
Ophthalmology
Pulmonology & Otorhinolaryngology
Otolaryngology, Ear-Nose, and Throat (ENT) and Maxillofacial Surgery
Podiatry
Urology
Summary
Additional Reading
Problems
DIAGNOSTIC APPLICATIONS OF LIGHT
Diagnostic Methods Using Light: Photophysical
Optical Microscopy
Various Microscopic Techniques
Near-Field Scanning Optical Microscope
Spectroscopy
Holographic Imaging
Polarization Imaging
Transillumination Imaging
Optical Coherence Tomography
Ballistic Photon Imaging
Reflectometry
Evanescent Wave Imaging Applications
Medical Thermography
Photoacoustic Imaging
Tera Hertz Imaging
Summary
Additional Reading
Problems
Diagnostic Methods Using Light: Photochemical
Fluorescence Imaging
Ratio Fluorescence Microscopy
Raman Spectroscopy with NSOM Employed
Optical "Tongue"
Summary
Additional Reading
Problems
Diagnostic Methods Using Light: Photobiological
Immuno Staining ("Functional Imaging")
Immunofluorescence
Diagnostic Applications of Spectroscopy
Fiberoptic Sensors
Optical Coherence Tomography in Dentistry
Optical Biopsy
Determination of Blood Oxygenation
Electroluminescent Electro-Physiologic Mapping
Quantum Dots as Biological Fluorescent Markers
Compilation of the Optical Requirements for Wavelength Selection Based on the Desired Effects
Summary
Additional Reading
Problems
Biography
Robert Splinter, Brett A. Hooper
"An outstanding feature of the book is its carefully designed structure which makes it abundantly clear where required material is located . . . one should commend the high standard of production of the book; it is well laid out . . . Overall it is considered that acquisition of this book will be an excellent investment for anyone who wishes to gain an appreciation of the principles and applications of biomedical optics."
– Professor K. A. Shore, University of Wales, in Contemporary Physics, November 2007