1508 Pages
by
Routledge
A single source for accurate scientific information on herbal remedies! This comprehensive handbook (comprised of two volumes of 700+ pages each) provides a snapshot of 160 herbal products that have been tested in clinical trials. Details of the products and the clinical trials they underwent are here in an easy-to-read, at-a-glance format. Each botanical profile in The Handbook of Clinically... Read more
VOLUME 1
- About the Editor
- Contributors
- Preface
- Acknowledgments
- Editor’s Note
- PART I: FUNDAMENTALS OF HERBAL MEDICINE
- Chapter 1. History and Regulation of Botanicals in the United States (Loren D. Israelsen and Marilyn Barrett)
- Introduction
- History
- DSHEA Explained
- Drugs: OTC and Rx
- Prospectus
- Chapter 2. Product Definition Deficiencies in Clinical Studies of Herbal Medicines (Varro E. Tyler)
- Chapter 3. Identifying and Characterizing Botanical Products (Marilyn Barrett)
- Identifying Plants by Name
- Means of Assuring Plant Identity
- Preparations and Formulations
- Dose
- Bioavailability
- Guidelines
- Appendix: Preparations and Formulations
- Chapter 4. Standardization of Botanical Preparations: What It Does and Does Not Tell Us (Uwe Koetter and Marilyn Barrett)
- Introduction
- Standardization of Therapeutic Activity
- Standardization to Meet a Chemical Norm
- Standardization As a Reflection of Quality Assurance Programs
- Guidance
- Situation in the Marketplace
- Perspective
- Chapter 5. The Importance and Difficulty in Determining the Bioavailability of Herbal Preparations (Anton Biber and Friedrich Lang)
- Chapter 6. Borrowed Science and Phytoequivalence: Can Two Herbal Products Be Judged Equivalent? (Marilyn Barrett)
- Chemical or Pharmaceutical Equivalency
- Bioequivalency or Therapeutic Equivalency
- Application of the Concepts, Ginkgo As an Example
- Meta-Analyses
- Perspective
- Chapter 7. Determining Efficacy of Herbal Preparations (Tieraona Low Dog)
- Observational Medicine
- Evidence-Based Medicine
- Summary
- Chapter 8. Evaluating Safety of Herbal Preparations (Ezra Béjar, Joseph M. Betz, and Marilyn Barrett)
- Evaluation of Safety
- Adverse Reactions
- Adverse-Event Reporting Systems
- Categorization According to the Degree of Safety
- Product Quality As an Aspect of Safety
- Contraindications
- Drug-Herb Interactions
- Improving Our Knowledge of Safety
- Chapter 9. Conducting Clinical Trials on Herbal Dietary Supplements in North America: Commercialization, Confidence, and Conflicts (Anthony L. Almada)
- The Spirit to Sponsor: Is There an Adequate Economic Incentive to Fund Research?
- Extracting Value from Science
- Competitor Kevlar: Preventing Piracy of Product-Specific Data
- How Much Data Is Enough?
- We Have DataNow What?
- Who Has Science and How Did They Acquire It?
- Conclusion
- Chapter 10. Motives for Conducting Clinical Trials on Botanicals in Europe: A Focus on Germany (Joerg Gruenwald and Stefan Spiess)
- Chapter 11. Pharmacopoeias and Botanical Monographs (Marilyn Barrett, Roy Upton, and V. Srini Srinivasan)
- United States Pharmacopeia and National Formulary (USP-NF)
- American Herbal Pharmacopoeia (AHP) and Therapeutic Compendium
- European Pharmacopoeia (EP)
- British Herbal Pharmacopoeia (BHP) and British Herbal Compendium (BHC)
- American Herbal Pharmacopoeia (AHP) and Therapeutic Compendium
- German Commission E
- European Scientific Cooperative of Phytotherapy (ESCOP)
- Chinese Pharmacopoeia
- African Pharmacopoeia
- The Pharmacopoeia of Japan
- African Pharmacopoeia
- The Pharmacopoeias of India
- World Health Organization (WHO)
- Other Pharmacopoeias
- Summary and Perspective
- Sources of Pharmacopoeias
- PART II: METHODS
- Chapter 12. Methods of Product and Trial Inclusion and Evaluation (Marilyn Barrett)
- Gathering Information on Products and Trials
Biography
Marilyn Barrett






