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Handbook of Industrial Mycology

Edited by Zhiqiang An

Series Editor: Joan W. Bennett

Contributors: Till Hornbogen, Christopher L. Schardl, Gary A. Payne, Nancy P. Keller, Katsuhiko Ando, Jonathan Arnold, Gerald Bills, Michel Chartrain, Neal C. Connors, Arnold L. Demain, Juan Manuel Dominguez, Yuataka Ebizuka, Guy Harris, C. R. Hutchinson, Jay D. Keasling, Shidong Li, Xingzhong Liu, Prakash Masurekar, Christine McCallum, Marvin Schulman, Toru Okuda, Fernando Pelaez, Berry Scott, Marc Stadler, Jan Tkacz, Jae-Hyuk Yu, Ningyan Zhang, Rainer Zocher, Xiang Ye

Published August 30th 2004 by CRC Press – 1,159 pages

Series: Mycology

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Description

Several excellent books have been published that address one or more aspects of the diverse field of industrial mycology, but none of them cover the entire process of fungal bioactive metabolites discovery. Until now. The Handbook of Industrial Mycology provides, in one volume, an overview of recent developments in industrial mycology with emphasis on the discovery of bioactive metabolites and, most importantly, their underlying biology and genetics. Two additional features distinguish this book from other books in the field: 1) most chapters are prepared using experimental data to illustrate theories and 2) the authors provide methodologies and experimental protocols in their chapters.

Presenting a comprehensive overview of recent advances, the book provides a framework of basic methods, tools, and organizational principles for channeling fungal germplasm into the academic, pharmaceutical, and enzyme discovery laboratories. It covers the complex range of processes involved in the discovery, characterization, and profiling of bioactive fungal metabolites. The book includes examples of several recently marketed fungal metabolites and explores the impact of fungi on applications in the pharmaceutical, food and beverage, agricultural, and agrochemical industries.

Reviews

"This book is a well-organized and superbly researched

publication well suited for researchers engaged in further studying the biochemical basis for the functional effects of tea extracts or components and for healthcare professionals who are inclined to use traditional medicines…"

Journal of Natural Products

"An's book is in the same series of the two edited by Arora and is very much one of a triumvirate, largely complementary rather than duplicatory in content. …Especially well-researched, comprehensive, and authoritative, is the review of 'Biological activities of fungal metabolites' (Peláez). …my recommendation has to be the three superb and largely complementary Marcel Dekker volumes, carefully put together under the keen eye of the series editor, Joan W. Bennett."

-Mycological Research, Oct. 2005

"…the handbook stands alone as a hefty reference guide to industrial exploration of fungi. …International literature is well-represented."

-E-Streams, Vol. 8, No. 9

"The enthusiastic introductory chapter is followed by a wealth of information about the nature, biological activity and taxonomic significance of fungal metabolites… .The book is packed with information and the Editor is to be congratulated on getting together an extensive team of contributors. Although most of the book is concerned with the beneficial use of fungi, one chapter is devoted to a general account of mycotoxins. …this book should surely be on the shelves of any laboratory involved with fungal biotechnology and is an excellent source of information for those involved with teaching and research on fungi."

-Microbiology Today

Contents

MYCOLOGY, INDUSTRIAL MYCOLOGY, AND FUNGAL BIOLOGY

Industrial Mycology: Past, Present and Future

Phylogeny of the Fungal Kingdom and Fungal-like Eukaryotes

Biological Activities of Fungal Metabolites

Cell Cycle Regulation in Morphogenesis and Development of Fungi

Agrobacterium-Mediated Transformation of Filamentous Fungi

FUNGAL SECONDARY METABOLITES DISCOVERY

Fungal Germplasm for Drug Discovery and Industrial Applications

Expression of Cosmid-Size DNA of Slow-Growing Fungi in Aspergillus nidulans for Secondary Metabolite Screening

The Isolation and Structure Elucidation of Fungal Metabolites

PCR-Based Data and Secondary Metabolites as Chemotaxonomical Markers in High Throughput Screening for Bioactive Compounds from Fungi

Screening for Biological Activities in Fungal Extracts

Sordarins, Inhibitors of Fungal Elongation Factor 2

BIOSYNTHESIS OF FUNGAL SECONDARY METABOLITES

Secondary Metabolite Gene Clusters

The Aflatoxin Biosynthetic Pathway

Indole-Diterpene Biosynthesis in Ascomycetous Fungi

Loline and Ergot Alkaloids in Grass Endophytes

Biosynthesis of N-methylated peptides in fungi

The Molecular Genetics of Lovastatin and Compactin Biosynthesis

The Aspergillus nidulans Polyketide Synthase WA

FERMENTATION, STRAIN IMPROVEMENT, AND BIOCONVERSION

Pneumocandin B0 Production by Fermentation of the Fungus Glarea lozoyensis: Physiological and Engineering Factors Affecting Titer and Structural-Analogue Formation

Strain Improvement for the Production of Secondary Metabolites

Fungal Bioconversions: Applications to the Manufacture of Pharmaceuticals

METABOLIC ENGINEERING

Metabolomics

Metabolic Engineering Fungal Secondary Metabolic Pathways

HETEROLOGOUS PROTEIN AND ENZYME EXPRESSION IN FUNGI

Heterologous Protein and Enzyme Expression in Fungi

MYCOTOXIN

Toxigenic Fungi and Mycotoxin

FUNGI IN BIOLOGICAL CONTROL

Biochemical Basis of Fungi in Biocontrol of Plant Diseases

Name: Handbook of Industrial Mycology (Hardback) – CRC Press 
Description: Edited by Zhiqiang AnSeries Editor: Joan W. BennettContributors: Till Hornbogen, Christopher L. Schardl, Gary A. Payne, Nancy P. Keller, Katsuhiko Ando, Jonathan Arnold, Gerald Bills, Michel Chartrain, Neal C. Connors, Arnold L. Demain, Juan Manuel Dominguez, Yuataka Ebizuka, Guy Harris, C. R. Hutchinson, Jay D. Keasling, Shidong Li, Xingzhong Liu, Prakash Masurekar, Christine McCallum, Marvin Schulman, Toru Okuda, Fernando Pelaez, Berry Scott, Marc Stadler, Jan Tkacz, Jae-Hyuk Yu, Ningyan Zhang, Rainer Zocher, Xiang Ye. Several excellent books have been published that address one or more aspects of the diverse field of industrial mycology, but none of them cover the entire process of fungal bioactive metabolites discovery. Until now. The Handbook of Industrial Mycology...
Categories: Botany, Microbiology, Natural Products