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Drug Delivery Systems, Second Edition
2nd Edition
By Vasant V. Ranade, Mannfred A. Hollinger, John B. Cannon
- Price: $239.95
- Binding/Format: Hardback
- ISBN: 978-0-8493-1433-9
- Publish Date: August 26th 2003
- Imprint: CRC Press
- Pages: 464 pages
Series: Pharmacology and Toxicology: Basic and Clinical Aspects
Description
Drug delivery technologies represent a vast and vital area of Research and Development. The demand for innovative drug delivery systems continues to grow, and this growth continues to drive new developments.
Building on the foundation provided by the first edition, Drug Delivery Systems, Second Edition covers the latest developments in both industry and academia.
New in this edition:
Written in a straightforward, clear, and concise manner, the author provides a global perspective on current and future advances and market opportunities. Drug Delivery Systems, Second Edition answers the need for comprehensive information in a single resource for anyone venturing into this area of drug development.
Contents
SITE-SPECIFIC DRUG DELIVERY
Site-Specific Drug Delivery Using Liposomes as Carriers
Introduction
Liposomes in Drug Delivery
The Liposome-Drug Concept
Liposomes as Carriers of Therapeutic Agents
Recent Advances
Concluding Remarks
Site Specific Drug Delivery Utilizing Monoclonal Antibodies
Introduction
Production of Monoclonal Antibodies
Drug-Monoclonal Antibody Conjugates for Drug Targeting
Recent Studies with Monoclonal Antibodies
Conclusion and Basis for Future Trends
References
POLYMERS, IMPLANTABLE DRUG DELIVERY
Role of Polymers in Drug Delivery
Introduction
Currently Available Polymers
Soluble Polymers
Biodegradable or Bioerodible Polymers
Mucoadhesive Polymers
Polymers Containing Pendant Substituents
Matrix Systems
Heparin Releasing Polymers
Ionic Polymers
Oligomers
Miscellaneous
Recent Advances
Conclusion
Implants in Drug Delivery
Introduction
Insulin Delivery as a Model Implant Pump System
Implants for Contraception
ORAL DRUG DELIVERY
Oral Drug Delivery
Introduction
Features of the GI Tract
Targeting of Drugs in the GI Tract
Design and Fabrication of Oral Delivery systems
Survey of Oral Controlled Release Products
Recent Advances
Conclusion
References
TRANSDERMANL, INTRANASAL, OCULAR, AND MISCELLANEOUS DRUG DELIVERY
Transdermal Drug Delivery
Introduction
Structure of Human Skin
Theoretical Advantages of the Transdermal Route
Optimization of Percutaneous Absorption
Theory for Penetration-Enhancer Activity
Development of the Transdermal Therapeutic System
Examples of Transdermal Applications
Transdermal Controlled-Release Products and Devices
Recent Advances
Conclusion
References
Intranasal and Ocular Drug Delivery
Intranasal Drug Delivery
Ocular Drug Delivery
References
Miscellaneous Forms of Drug Delivery
Introduction
Prodrugs
Infusion Devices
Insulin Delivery
Parenteral Prolonged Action Dosage Forms
Summary
REGULATORY CONSIDERATIONS AND GLOBAL OUTLOOK
Regulatory Considerations for Drug Delivery Systems
Introduction
Current Status of Drug Delivery Technology
Submission of Documents for Manufacture and Quality
Drug Delivery Industry and the Global Outlook
INDEX