The Laboratory Rat

Description

Laboratory animals, including rats, play an important role in biomedical research and advances. The humane care and management of these animals is an ongoing concern. This guide was created especially for individuals performing research with laboratory rats whose duties include animal facility management, animal husbandry, regulatory compliance, and technical procedures involved with their research. Basic information and common procedures are presented in detail.

Contents

Important Biological Features

Introduction

Nomenclature

Behavior

Anatomical and Physiologic Features

Hematology and Clinical Chemistry

Reproduction

Husbandry

Housing

Environmental Enrichment

Nutrition

Sanitation

Transportation

Quality Control

Identification and Records

Management

Regulatory Agencies and Compliance

Voluntary Accreditation

Occupational Health and Zoonotic Diseases

Veterinary Care

Physical Examination

Diagnostic Imaging

Diseases of Laboratory Rats

Bacterial Diseases

Viral Diseases

Parasitic Disease

Neoplastic Disease

Age-Related Lesions and Miscellaneous Conditions

Other Disease Conditions

Disease Treatment and Control

Prevention of Infectious Disease

Anesthesia and Analgesia

Aseptic Surgery

Preoperative Issues

Operative Issues

Postoperative Issues

Euthanasia

Experimental Methodology

Restraint

Sampling Techniques

Compound Administration

Other Techniques

Common Research Uses

Other Rats Used in Research

Necropsy

Resources

Organizations

Publications

Electronic Resources

Vendors

References

OTI#1:

Related Subjects

1. Lab Animal Science
2. Neuroscience
3. Psychiatry
4. Laboratory Animal Science
5. Neuroscience
6. Psychiatry