1st Edition

Pediatric Tumors Immunological and Molecular Markers

By John T. Kemshead Copyright 1989
199 Pages
by CRC Press

198 Pages
by CRC Press

200 Pages
by CRC Press

This monograph explains the considerable impact that monoclonal antibodies and molecular probes have had on the diagnosis of tumor types and sub-types. It explains how radiolabelled monoclonal antibodies have also been used as imaging agents to try to improve the oncologist's ability to define residual tumor deposits after combination chemo/radiotherapy. Finally, the childhood malignancies that... Read more
1. Pathology and Epidemiology 2. Monoclonal Antibodies used for Diagnosis of Small Round Cell Tumors of Childhood 3. An Immunohistological Approach to Differential Diagnosis of Childhood Brain Tumors 4. Serologic Studies using Monoclonal and Polyclonal Antibodies — Their Diagnostic and Prognostic Usefulness 5. Ganglioside GD2 Specific Antibodies in the Diagnosis and Therapy of Human Neuroblastoma 6. The Development of Targeted Radiotherapy for Treatment of Small Round Cell Tumors of Childhood 7. Monoclonal Antibodies as Agents to Purge Tumor Cells from Bone Marrow: Laboratory and Clinical Experiences 8. Molecular Approaches Toward the Isolation of Pediatric Cancer Predisposition Genes 9. Gene Rearrangement in Leukemias and Lymphomas 10. The N-Myc Oncogene in Pediatric Tumors: Diagnostic, Prognostic, and Biological Aspects

Biography

John T Kemshead