1st Edition
Molecular, Cellular, and Tissue Engineering
MOLECULAR BIOLOGY
Historical Perspective and Basics of Molecular Biology; Nathan R. Domagalski and Michael Domach
Biomolecular Interactions; Gordon Rule
Recent Advances in DNA Separations: Plasmid Purification, Rapid Electrophoresis, and Affinity-Based Recovery; James W. Schneider and Jeffrey M. Savard
Systems and Technology Involving Bacteria; Nicole Bleckwenn and William Bentley
Expression in Mammalian Cells; Tina Sauerwald and Michael Betenbaugh
DNA Vaccines Production and Engineering; Michael M. Domach, Jonathan W. Meade, and Mohammad A. Ataai
TRANSPORT PHENOMENA AND BIOMIMETIC SYSTEMS
Biomimetic Systems: Concepts, Design, and Emulation; Robert J. Fisher
Transport/Reaction Processes in Biology and Medicine; E. N. Lightfoot
Microvascular Heat Transfer; James W. Baish
Fluid Dynamics for Bio Systems: Fundamentals and Model Analysis; Robert A. Peattie and Robert J. Fisher
Animal Surrogate Systems; Michael L. Shuler, Sarina G. Harris, Xinran Li, and Mandy B. Esch
Arterial Wall Mass Transport: The Possible Role of Blood Phase Resistance in the Localization of Arterial Disease; John M. Tarbell and Yuchen Qiu
Transport Phenomena and the Microenvironment; Robert J. Fisher and Robert A. Peattie
Transport and Drug Delivery through the Blood–Brain Barrier and Cerebrospinal Fluid; Bingmei M. Fu
Interstitial Transport in the Brain: Principles for Local Drug Delivery; W. Mark Saltzman
Surfactant Transport and Fluid–Structure Interactions during Pulmonary Airway Reopening; David Martin, Anne-Marie Jacob, and Donald P. Gaver III
PHYSIOLOGICAL MODELING, SIMULATION, AND CONTROL
Modeling Strategies and Cardiovascular Dynamics; Joseph L. Palladino, Gary M. Drzewiecki, and Abraham Noordergraaf
Compartmental Models of Physiological Systems; Claudio Cobelli, Giovanni Sparacino, Maria Pia Saccomani, Gianna Maria Toffolo, and Andrea Caumo
Cardiovascular Models and Control; Madhusudan Natarajan, Fernando Casas, and W.D. Timmons
Respiratory Models and Control; Chi-Sang Poon
Biomimetic Approaches to Physiological Control; James J. Abbas and Amit Abraham
Methods and Tools for Identification of Physiologic Systems; Vasilis Z. Marmarelis
Modeling Vascular Vibrations: Autoregulation and Vascular Sounds; Gary M. Drzewiecki, John K.-J. Li, and Abraham Noordergraaf
External Control of Movements; Dejan B. Popovic´ and Mirjana B. Popovic
The Fast Eye Movement Control System; John Denis Enderle
A Comparative Approach to Analysis and Modeling of Cardiovascular Function; John K.-J. Li, Ying Zhu, and Abraham Noordergraaf
A Biomedical and Biophysical Approach to the Science in Cardiopulmonary Resuscitation; Gerrit J. Noordergraaf, Igor W. F. Paulussen, Alyssa Venema, Gert Jan Scheffer, and Abraham Noordergraaf
Kinematic Modeling of Left Ventricular Diastolic Function; Leonid Shmuylovich, Charles S. Chung, and Sándor J. Kovács
STEM CELL ENGINEERING: AN INTRODUCTION
Engineering the Pluripotent Stem Cell Niche for Directed Mesoderm Differentiation; Céline L. Bauwens, Kelly A. Purpura, and Peter W. Zandstra
Cell Mechanobiology in Regenerative Medicine: Lessons from Cancer; Badriprasad Ananthanarayanan and Sanjay Kumar
Systems-Engineering Principles in Signal Transduction and Cell-Fate Choice; Karin J. Jensen, Anjun K. Bose, and Kevin A. Janes
Biomaterial Scaffolds for Human Embryonic Stem Cell Culture and Differentiation; Stephanie Willerth and David Schaffer
Stem Cells and Regenerative Medicine in the Nervous System; Shelly Sakiyama-Elbert
Stem Cells and Regenerative Medicine for Treating Damaged Myocardium; Rohini Gupta, Kunal Mehtani, Kimberly R. Kam, and Kevin E. Healy
Stem Cells and Hematopoiesis; Krista M. Fridley and Krishnendu Roy
Synthetic Biomaterials and Stem Cells for Connective Tissue Engineering; Ameya Phadke and Shyni Varghese
Derivation and Expansion of Human Pluripotent Stem Cells; Sean P. Palecek
Bioreactors for Stem Cell Expansion and Differentiation; Carlos A. V. Rodrigues, Tiago G. Fernandes, Maria Margarida Diogo, Cláudia Lobato da Silva, and Joaquim M. S. Cabral
TISSUE ENGINEERING
Strategic Directions; Peter C. Johnson
Silks; Monica A. Serban and David L. Kaplan
Calcium Phosphates; Kemal Sariibrahimoglu, Joop G.C. Wolke, Sander C.G. Leeuwenburgh, and John A. Jansen
Engineered Protein Biomaterials; Andreina Parisi-Amon and Sarah C. Heilshorn
Synthetic Biomaterials; Joshua S. Katz and Jason A. Burdick
Growth Factors and Morphogens: Signals for Tissue Engineering; A. Hari Reddi
Signal Expression in Engineered Tissues; Martha O. Wang and John P. Fisher
Pluripotent Stem Cells; Todd C. McDevitt and Melissa A. Kinney
Hematopoietic Stem Cells; Ian M. Kaplan, Sebastien Morisot, and Curt I. Civin
Mesenchymal Stem Cells; Pamela C. Yelick and Weibo Zhang
Nanobiomaterials for Tissue Engineering; Pramod K. Avti, Sunny C. Patel, Pushpinder Uppal, Grace O’Malley, Joseph Garlow, and Balaji Sitharaman
Biomimetic Approaches in Tissue Engineering; Indong Jun, Min Sup Kim, Ji-Hye Lee, Young Min Shin, and Heungsoo Shin
Molecular Biology Techniques; X.G. Chen, Y.L. Fang, and W.T. Godbey
Biomaterial Mechanics; Kimberly M. Stroka, Leann L. Norman, and Helim Aranda-Espinoza
Mechanical Conditioning; Elaine L. Lee and Horst A. von Recum
Micropatterned Biomaterials for Cell and Tissue Engineering; Murugan Ramalingam and Ali Khademhosseini
Drug Delivery; Prinda Wanakule and Krishnendu Roy
Gene Therapy; C. Holladay, M. Kulkarni, W. Minor, and Abhay Pandit
Nanotechnology-Based Cell Engineering Strategies for Tissue Engineering and Regenerative Medicine Applications; Joaquim Miguel Oliveira, João Filipe Mano, and Rui Luís Reis
Cell Encapsulation; Stephanie J. Bryant
Coculture Systems for Mesenchymal Stem Cells; Song P. Seto and Johnna S. Temenoff
Tissue Engineering Bioreactors; Sarindr Bhumiratana, Elisa Cimetta, Nina Tandon, Warren Grayson, Milica Radisic, and Gordana Vunjak-Novakovic
Shear Forces; Jose F. Alvarez-Barreto, Samuel B. VanGordon, Brandon W. Engebretson, and Vasillios I. Sikavitsas
Vascularization of Engineered Tissues; Monica L. Moya and Eric M. Brey
Biomedical Imaging of Engineered Tissues; Nicholas E. Simpson and Athanassios Sambanis
Multiscale Modeling of In Vitro Tissue Cultivation; Kyriacos Zygourakis
Bone Engineering; Lucas A. Kinard, Antonios G. Mikos, and F. Kurtis Kasper
Dental and Craniofacial Bioengineering; Hemin Nie and Jeremy J. Mao
Tendon and Ligament Engineering; Nicholas Sears, Tyler Touchet, Hugh Benhardt, and Elizabeth Cosgriff-Hernández
Cartilage Tissue Engineering; Emily E. Coates and John P. Fisher
TMJ Engineering; Michael S. Detamore
Interface Tissue Engineering; Helen H. Lu, Nora Khanarian, Kristen Moffat, and Siddarth Subramony
The Bioengineering of Dental Tissues; Rena N. D’Souza, Katherine R. Regan, Kerstin M. Galler, and Songtao Shi
Tissue Engineering of the Urogenital System; In Kap Ko, Anthony Atala, and James J. Yoo
Vascular Tissue Engineering; Laura J. Suggs
Neural Engineering; Yen-Chih Lin and Kacey G. Marra
Tumor Engineering: Applications for Cancer Biology and Drug Development; Joseph A. Ludwig and Emily Burdett
ARTIFICIAL ORGANS
Artificial Heart and Circulatory Assist Devices; Gerson Rosenberg
Cardiac Valve Prostheses; Arjunon, Neelakantan Saikrishnan, and Ajit P. Yoganathan
Artificial Lungs; Keith E. Cook, Timothy M. Maul, and William J. Federspiel
Blood Substitutes; Amy G. Tsai, Pedro Cabrales, and Marcos Intaglietta
Liver Support Systems; Matthew S. Chang and Robert S. Brown
Peritoneal Dialysis Equipment; Carlo Crepaldi, Francesca Katiana Martino, Maria Pia Rodighiero, and Claudio Ronco
Artificial Skin and Dermal Equivalents; Dennis P. Orgill, Raul Cortes, and Ioannis V. Yannas
DRUG DESIGN, DELIVERY SYSTEMS, AND DEVICES
Physiological Barriers to Drug Transport; Fan Yuan
Nucleic Acid Aptamers in Drug Delivery; Mark R. Battig, Jing Zhou, and Yong Wang
Dendrimers for Drug Delivery; Giridhar Thiagarajan and Hamidreza Ghandehari
Noninvasive Targeted Protein and Peptide Drug Delivery; Pradeep K. Karla, Durga K. Paturi, Nanda K. Mandava, Animikh Ray, Sulabh Patel, Ranjana Mitra, and Ashim K. Mitra
Environment-Responsive Hydrogels for Drug Delivery; Byung Kook Lee, Jong-Ryoul Kim, Kinam Park, and Yong Woo Cho
Biodegradable PLGA Scaffolds for Growth Factor Delivery; Yusef Khan and Cato Laurencin
PERSONALIZED MEDICINE
Physiogenomic Contours: The Application of Systems Biology for Engineering Personalized Health Care; Andreas Windemuth, Richard L. Seip, and Gualberto Ruaño
The Evolution of Massively Parallel Sequencing Technologies: Facilitating Advances in Personalized Medicine; Ian Toma, Georges St. Laurent, III, Samuel Darko, and Timothy A. McCaffrey
Computational Methods and Molecular Diagnostics in Personalized Medicine; Roland Valdes, Jr. and Mark W. Linder
Need for Point-of-Care Testing Devices for Cardiac Troponin in Patients with Acute Coronary Syndromes; Alan H.B. Wu and Amy E. Herr
ETHICS
An Introduction to Bioethics and Ethical Theory for Biomedical Engineers; D. John Doyle
Biography
Joseph D. Bronzino is the founder and president of the Biomedical Engineering Alliance and Consortium (BEACON) in Hartford, Connecticut. He earned a PhD in electrical engineering from Worcester Polytechnic Institute in Massachusetts. Dr. Bronzino has received the Millennium Award from IEEE/EMBS and the Goddard Award from Worcester Polytechnic Institute for Professional Achievement. He is the author of more than 200 articles and 11 books.
Donald R. Peterson is a professor of engineering and dean of the College of Science, Technology, Engineering, Mathematics, and Nursing at Texas A&M University–Texarkana. He earned a PhD in biomedical engineering from Worcester Polytechnic Institute in Massachusetts. Dr. Peterson’s recent research focuses on measuring and modeling human, organ, and/or cell performance, including exposures to various physical stimuli and the subsequent biological responses. Dr. Peterson has published more than 50 journal articles and 12 reference books.






