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Handbook of Clinical Nanomedicine

From Bench to Bedside

Edited by Raj Bawa, Gerald F. Audette, Israel Rubinstein

Pan Stanford – 2014 – 800 pages

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    February 28th 2015
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The enormous advances in nanomedicine in the past decade have necessitated a growing need for an authoritative and comprehensive reference source that can be relied upon by scientists, clinicians, students, and industry and policy makers alike. The Handbook of Clinical Nanomedicine: From Bench to Bedside is designed to offer a global perspective on the wonders of nanomedicine.

The handbook aims to provide a broad survey of various interconnected topics pertaining to nanomedicine. It is intended to be a stand-alone, easily accessible volume that examines the entire "product wheel" from creation of nanomedical products to final market introduction, all accomplished in a user-friendly format. Specifically, everything from bio-nanomaterials and nanodevices from the R&D stage to patent protection, clinical regulatory aspects, and eventual commercialization is encompassed in this book. In addition to highlighting cutting-edge technologies, the book addresses critical topics such as ethics, safety and toxicity, environmental health, nanoeconomics, business strategy, licensing, intellectual property, FDA law, EPA law, and governmental policy issues. With contributions from international experts, the diverse team of editors has compiled a book that provides a unified perspective to these varied topics. While many books focus on nanomedicine, nanotechnology, or nanoscience, none provide the medical applications of nanotechnology with both a clinical and business angle. Furthermore, most of the currently available books on the market fail to highlight the truly global nature of nanomedicine.

The handbook, divided into four sections, provides a comprehensive road map of basic research in nanomedicine as well as clinical applications and commercialization activities. Each of the 45-plus chapters contains 10–20 key words, extensive tables, color figures, future projections, and an extensive list of references. The handbook is an essential reading for the novice and expert alike in fields such as medicine, law, biotechnology, pharmaceutical sciences, engineering, biomedicine, policy, future studies, ethics, intellectual property law, licensing, and toxicology. While bridging the gap between basic biomedical research, engineering, and medicine, the handbook provides an understanding of nanotechnology’s

  • use to solve medical problems
  • current applications and their potential
  • regulatory environment and policy issues
  • intellectual property, licensing, and business activities

It is clear that the well-known editors have skillfully selected and thoroughly edited each chapter to reflect the most updated information possible. The range of topics covered as well as the international selection of authors is truly impressive. Since the rapidly evolving field of nanomedicine is very diverse and covers physical, chemical, biological, and engineering aspects, the range of the contributing authors accurately reflects this. The book’s multidisciplinary approach and an in-depth focus on nanomedicine, pharmaceutical sciences, materials science, biomedical engineering, and biotechnology will attract a global audience. In short, Handbook of Clinical Nanomedicine: From Bench to Bedside promises to be a standard reference text in this expansive and interdisciplinary field. It is a timely addition to the literature on nanosciences and will undoubtedly serve as a catalyst to stimulate interest in this rapidly growing field.



Science at the nanoscale: Introduction and historical perspective

Song, Haur and Wee

Nanomedicine: Dynamic integration of nanotechnology with biomedical science

Lee, Solanki, Kim, Jung

Defining nanotechnology and nanomedicine – big issue in small science


Nano-therapeutics and the future of medicine

Bawa, Bawa and Mehra

Top ten recent nanomedical advances


Nanosystems, Nanodevices and Imaging Tools

Nanosizing approaches in drug delivery

Chavhan, Petkar and Sawant

Design and development of approved nanopharmaceutical products

Mansour, Park and Bawa

Designing nanocarriers for the effective treatment of cardiovascular diseases

Vaidya and Vyas

Nanoparticles for multi-modality diagnostic imaging and drug delivery

Lockhart and Ho

Magnetic nanoparticles in magnetic resonance imaging: A translational push toward theranostics

Ortega, Yankeelov and Giorgio

Atomic force microscopy for nanomedicine

Sharma and Gimzewski

Advances in the use of nanomedicine for medical imaging

Dearling and Packard

Image-based high-content analysis, stem cells and nanomedicines: A novel strategy for drug discovery

Solomesky, Adalist and Weil

AFM imaging and probing amyloid nanoaggergates


Intracellular transport and unpacking of polyplex nanoparticles

Rosenkranz, Khramtsov, Ulasov, Rodichenko and Sobolev

Cell and protein interactions with small-scale diamond materials

Narayan, Boehm and Monteiro-Riviere

Bacterial secretion systems: nanomachines for infection and genetic diversity

Shala, Ferarro and Audette

Viral nanoparticles: Tools for materials science and biomedicine

Steinmetz and Manchester

Clinical Applications

Polysaccharides as nanomaterials for therapeutics

Mizrahy and Peer Diwan

Aptamers in clinical trials

Kanwar, Roy, Kanwar and Bawa

Nanotechnology and the skin barrier: topical and transdermal nanocarrier-based delivery

Labouta and Schneider

Transdermal immunotherapy with synthetic pathogen-like nanomedicines and its clinical application towards the cure of HIV

Lorincz and Lisziewicz

Application of nanotechnology in non-invasive topical gene therapy

Esabahy, Jimena Loureiro and Foldvari

Nanocarriers in the therapy of inflammatory disease


Nanomedicine challenges in thrombosis


Nanomedicine for cardiovascular disease: Potentials and Challenges


Nanomedicine for acute lung injury/acute respiratory distress syndrome: a shifting paradigm?

Sadikot and Rubinstein

Multilayered nanoparticles for personalized medicine: translation into clinical markets


Carbon nanotubes as substrates for neuronal growth


Polymeric nanoparticles for cancer therapeutics

Verma, Rosen, Meerasa, Yoffe and Gu

Nanotechnology for radiation oncology

Sridhar, Berbeco, Cormack, and Makrigiorgos

Solid lipid nanoparticles and nanostructured lipid carriers for cancer therapy


Nanoparticles for brain cancer therapy

Agarwal, Tiwari, Agrawal

Complement activation: a capricious immune barrier to nanomedicine clinical application


Regulatory Issues, Toxicology, Intellectual Property and Nano-Ethics

Regulating nanomedicine at the FDA and EPA

Hartman, Bawa, Monica

Regulatory aspects of nanomedicine in Europe


Managing environmental and health risks in the nanotechnology industry


Toxicity of silicon dioxide nanoparticles in mammalian neural cells

Lai, Jaiswal, Lai, Jandhyam, Leung and Bhushan

An intellectual property primer for nanomedical researchers and engineers


Strategic intellectual property management – building IP portfolios


IP Valuation: principles and applications in the nanotechnology industry


Extending patent term for nanomedical inventions – A nexus between the FDA and the patent system


Technology transfer: An overview


Licensing issues in nanotechnology


The Tower of Babel: miscommunication within and about nanomedicine


Clinical nanobioethical problems: a value approach


The audience is the message: nanomedicine as apotheosis or damnatio memoriae


Name: Handbook of Clinical Nanomedicine: From Bench to Bedside (Hardback)Pan Stanford 
Description: Edited by Raj Bawa, Gerald F. Audette, Israel Rubinstein. The enormous advances in nanomedicine in the past decade have necessitated a growing need for an authoritative and comprehensive reference source that can be relied upon by scientists, clinicians, students, and industry and policy makers alike. The...
Categories: Biomedical Engineering, Nanoscience & Nanotechnology, Biomaterials