Active Phytochemicals from Chinese Herbal Medicines Anti-Cancer Activities and Mechanisms
Chinese herbal medicine represents complementary or adjunctive therapies that often can improve the efficacy of Western medicine to achieve the pharmacological effects, especially in cancer treatment. However, the combination of herbs with therapeutic drugs can raise potential health risk. Building a bridge between Western medicine and herbal medicines, Active Phytochemicals from Chinese Herbal Medicines: Anti-Cancer Activities and Mechanisms gives you useful information on how integrated medicines can work for cancer therapy. It discusses the therapeutic uses of phytochemicals, adverse effects, and interactions with (Western) cancer drugs.
The author takes a unique approach to integrated pharmacology of herbal medicines, examining the development of phytochemicals and their mechanisms of action in the context of the cancers and diseases they are used to treat. He covers biologic action of the active phytochemicals at the molecular, cellular, and organ levels. The book covers the principles of the interaction of phytochemicals and the related drug actions. It also addresses the common pathways affecting cancer development before discussing the phytochemical classes and specific phytochemicals that have been recently reported in journal papers for the management of cancer and other diseases.
Highlighting the increasingly important aspects of pharmacology, including health benefit and drawbacks of phytochemicals, the book presents the relevant background of the biochemistry of the cancer. It includes illustrations and tables with adverse reactions that highlight important issues related to phytochemical actions. These features and more make the book a useful reference on phytochemicals obtained from herbal medicines. It blends coverage of fundamental mechanisms of anti-cancer action and the use of phytochemicals to manage cancers and other human diseases, allowing you to explore how herbal medicines can enhance conventional protocols.
Overview: General Principles
Combination of Cancer Drugs
Plant-Derived Active Phytochemicals Show Various Biologic and Pharmacological Activities in Cancer
Therapeutic Benefits of Phytochemicals
Mechanism of Cancer Drug Action
Inhibition of Cancer Growth by Herbal Medicines
Herbal Formulations in Folk Medicine
Exploration of Herbal Medicine
List of Selected Phytochemicals
With a focus on cancer therapy, this book explores the ways in which conventional treatments can be combined with traditional Chinese herbal extracts to produce better outcomes. This is an innovative approach, as most accounts focus on one or other aspect. Chapters on combination drugs and plant-derived compounds known to be active against cancer are accompanied by others on the therapeutic benefits of phytochemicals, the mechanisms of cancer drug actions, and the ways in which they inhibit cancer growth.
The book also covers other areas such as the treatment and prevention of dementia; eight plant extracts are listed as showing promising effects either for cognitive symptoms, behavioural and psychological symptoms, or for cholinesterase inhibition.
Although this book is aimed primarily at research-level pharmacists, it also serves as a useful introduction to Chinese traditional medicine for a western audience including medical students. Each chapter has a full list of references, including many by Chinese authors, and the appendix contains a list of selected phytochemicals along with their chemical formulae.
- John Edmondson, Chromatographia, Volume 82, Issue 2