The only available text to focus primarily on Acute Respiratory Distress Syndrome (ARDS).
Thoroughly revised content and ten new chapters provide pulmonologists with the latest developments and applications of pharmacological and mechanical therapies needed to treat the debilitating and difficult condition of ARDS.
Highlights include:
- the definition, epidemiology, pathology, and pathogenesis of ARDS
- complications such as transfusion-related injury, and endothelium and vascular dysfunction
- the long-term outcomes of ARDS
- host defense and infection
- the latest developments in ARDS therapy: glucocorticoid therapy, surfactant therapy, mechanical ventilation, and mesenchymal stem cells
- predictive factors: gene expression profiling and biomarkers, and chemokines and cytokines
- advances in management strategies: fluid management, non-pulmonary and non-sepsis management, and glucose control
Definitions and Clinical Risk Factors
Marc Moss and B. Taylor Thompson
Epidemiology of Acute Lung Injury: A Public Health Perspective
Gordon D. Rubenfeld and Margaret J. Neff
Radiographic Findings of the Acute Respiratory Distress Syndrome
Philip C. Goodman and Desir´ee M. Qui˜nones
Pulmonary Pathology of ARDS: Diffuse Alveolar Damage
Lester Kobzik and Lynette Sholl
Pathogenesis of Acute Lung Injury: Experimental Studies
Rebecca M. Baron and Mark A. Perrella
Pathogenesis of Acute Lung Injury: Clinical Studies
Benedict C. Creagh-Brown and Timothy W. Evans
Apoptosis in the Pathogenesis and Resolution of Acute Lung Injury
Gustavo Matute-Bello and Thomas R. Martin
Pathogenesis of Ventilator-Induced Lung Injury
Franco Valenza, James A. Frank, Yumiko Imai, and Arthur S. Slutsky
Sepsis in the Acute Respiratory Distress Syndrome: Treatment Implications
Arthur P. Wheeler and Todd W. Rice
Transfusion-Related Acute Lung Injury
Mark R. Looney and Ognjen Gajic
Mechanisms of Fibroproliferation in Acute Lung Injury
Danielle Morse and Carol Feghali-Bostwick
Current Approaches and Recent Advances in the Genetic Epidemiology of Acute Lung Injury/Acute Respiratory Distress Syndrome
Michelle NG Gong and David C. Christiani
Gene Expression Profiling and Biomarkers in ARDS
Judie Howrylak and Augustine M. K. Choi
Resolution of Alveolar Edema: Mechanisms and Relationship to Clinical Acute Lung Injury
Lorraine B. Ware and Michael A. Matthay
Lung Vascular Dysfunction and Repair in Acute Lung Injury: Role of the Endothelial Cytoskeleton
Gabriel D. Lang, Eddie T. Chiang and Joe G. N. Garcia
Surfactant Therapy in the Acute Respiratory Distress Syndrome
Roger G. Spragg and James F. Lewis
Prone Position in ARDS
Antonio Anzueto and Luciano Gattinoni
Mechanical Ventilation in the Acute Respiratory Distress Syndrome
Roy G. Brower and Laurent Brochard
Fluid Therapy and HemodynamicMonitoring in Acute Lung Injury
Carolyn S. Calfee, Naveen Gupta, and Michael A. Matthay
Pathogenesis of Sepsis and Sepsis-Induced Acute Lung Injury
Estelle S. Harris, Matthew T. Rondina, Hansj¨org Schwertz, Andrew S. Weyrich, and Guy A. Zimmerman
Cell-Based Therapy for Acute Lung Injury and Acute Respiratory Distress Syndrome
Naveen Gupta, Jae-Woo Lee, and Michael A. Matthay
Chemokines and Cytokines in ARDS
Michael P. Keane, Emer Kelly, and Robert M. Strieter
Biography
Augustine M.K. Choi
