388 pages | 242 B/W Illus.
Adaptive Optics for Biological Imaging brings together groundbreaking research on the use of adaptive optics for biological imaging. The book builds on prior work in astronomy and vision science. Featuring contributions by leaders in this emerging field, it takes an interdisciplinary approach that makes the subject accessible to nonspecialists who want to use adaptive optics techniques in their own work in biology and bioengineering.
Organized into three parts, the book covers principles, methods, and applications of adaptive optics for biological imaging, providing the reader with the following benefits:
Since the sample is an integral part of the optical system in biological imaging, the field will benefit from participation by biologists and biomedical researchers with expertise in applied optics. This book helps lower the barriers to entry for these researchers. It also guides readers in selecting the approach that works best for their own applications.
"Overall, this is an excellent book, which achieves its stated primary goal. … Without reservations, this is a book I would recommend to anyone who wishes to start learning about the principles and potential of AO in this field."
—Biomedical Engineering OnLine
"The strength of the book is the delicate balance of theory and instrumentation and applications. … Another example of the comprehensive nature of the chapters is a critical discussion of the adaptive optical elements. … Adaptive Optics for Biological Imaging is a good place to start to understand the problem (aberrations induced by the instrument, the objective, and the specimen and its preparation and mounting in the microscope), and the various instrumental and computational approaches to approach a solution (minimize the significant aberrations)."
—Barry R. Masters, Journal of Biomedical Optics, Volume 18, July 2013
"This book is a broad and comprehensive introduction to the use of adaptive optics (AO) in biological microscopy. It provides a much-needed entrée to the field and includes not only the basics and general principles but also discussion of practical implementations and key application areas."
—From the Foreword by Professor Austin Roorda, University of California at Berkeley, and Professor Claire Max, University of California at Santa Cruz
Principles of Wave Optics
Donald T. Gavel
Principles of Geometric Optics
Theory of Image Formation
Aberrations and Benefit of Their Correction in Confocal Microscopy
Specimen-Induced Geometrical Distortions
Simulation of Aberrations
Overview of Adaptive Optics in Biological Imaging
Elijah Y.S. Yew and Peter T.C. So
Adaptive Optics System Alignment and Assembly
Diana C. Chen
Applications: Indirect Wavefront Sensing
Sensorless Adaptive Optics for Microscopy
Martin J. Booth and Alexander Jesacher
Implementation of Adaptive Optics in Nonlinear Microscopy for Biological Samples Using Optimization Algorithms
John M. Girkin
AO Two-Photon Fluorescence Microscopy Using Stochastic Parallel Descent Algorithm with Zernike Polynomial Basis
Pupil-Segmentation-Based Adaptive Optics for Microscopy
Na Ji and Eric Betzig
Applications: Direct Wavefront Sensing
Coherence-Gated Wavefront Sensing
Jonas Binding and Markus Rückel
Adaptive Optics in Wide-Field Microscopy
Peter Kner, Zvi Kam, David A. Agard, and John Sedat
Biological Imaging and Adaptive Optics in Microscopy
Elijah Y.S. Yew, Jae Won Cha, Jerome Ballesta, and Peter T.C. So
Adaptive Optical Microscopy Using Direct Wavefront Measurements
Oscar Azucena, Xiaodong Tao, and Joel Kubby