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Adhesion Molecules in Allergic Disease: 1st Edition (Hardback) book cover

Adhesion Molecules in Allergic Disease

1st Edition

By Bruce S. Bochner

CRC Press

440 pages

Purchasing Options:$ = USD
Hardback: 9780824798369
pub: 1997-03-31

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This unique resource-the first book of its kind exclusively devoted to the subject-offers timely coverage of the cells, mechanisms, and proteins involved in allergic inflammation, emphasizing the latest advances in local cell recruitment.



…figures are clearly illustrative, and complex concepts, such as the multistep recruitment paradigm, are presented in a way which can be easily understood.

…will be useful for both scientists within the various fields of inflammation research and physicians with special interest in allergic diseases.


"…this is the first book exclusively devoted to a defined immunopathological process (allergic inflammation) that produces a variety of clinical entitites….a useful resource for students, basic scientists and clinicians who wish to be conversant with current developments in the immunobiology of CAMs and allergic diseases….[and] in the promising field of anti-adhesive therapy, particularly of allergic inflammation.

"-Immunology Today

Table of Contents

General Adhesion Molecule Biology

Overview of Cell Adhesion Molecules and Their Antagonism, Arthur Kavanaugh

The Endothelium in Leukocyte Recruitment, Francis W. Luscinskas

Epithelial Cells: Phenotype, Substratum, and Mediator Production, Albert J. Polito and David Proud

Integrins, Integrin Regulators, and the Extracellular Matrix: The Role of Signal Transduction and Leukocyte Migration, Stephen W. Hunt III, Sirid-Aimée Kellerman, and Yoji Shimizu

Pathways of Cell Recruitment to Mucosal Surfaces, Michael J. Briskin

In Vitro Studies of Basophils and Mast Cells

Phenotypic and Functional Characteristics of Adhesion Molecules on Human Basophils, Sarbjit S. Saini, Kenji Matsumoto, and Bruce S. Bochner

Integrin-Dependent Responses in Human Basophils, Jane A. Warner, Kirsty Rich, and Kirstin Goldring

Cell Adhesion Molecules in Mast Cell Adhesion and Migration, Harissios Vliagoftis and Dean D. Metcalfe

In Vitro Studies of Eosinophils

Eosinophil-Endothelial Interactions and Transendothelial Migration, Motohiro Ebisawa, Bruce S. Bochner, and Robert P. Schleimer

Eosinophil Interactions with Extracellular Matrix Proteins: Effects on Eosinophil Function and Cytokine Production, Garry M. Walsh and Andrew J. Wardlaw

Eosinophil-Epithelial Interactions and Transepithelial Migration, Mary K. Schroth, James M. Stark, Julie B. Sedgwick, and William W. Busse

Regulation of Eosinophil Mediator Release by Adhesion Molecules, Hirohito Kita

In Vivo Studies

Mast Cell Activation and Leukocyte Recruitment Responses Into Skin Sites: Role of Cell Adhesion Molecules, Michael D. Ioffreda and George F. Murphy

Mast Cell Activation and Leukocyte Rolling Responses, Paul Kubes

Adhesion Pathways Controlling Recruitment Responses of Lymphocytes During Allergic Inflammatory Reactions In Vivo, Donald Y. M. Leung and Louis J. Picker

Expression of Cell Adhesion Molecules in Asthma, Stephen Montefort and Stephen T. Holgate

Expression of Cell Adhesion Molecules in Eosinophilic Disorders of the Skin and Nose, Lisa A. Beck and Steve N. Georas

Expression of Cell Adhesion Molecules in Allergic Disorders of the Eye, Giorgio Walter Canonica, Antonio Scordamaglia, Francesca Paolieri, Nicolò Fiorino, Giovanni Passalacqua, and Giorgio Ciprandi

Adhesion Molecules, Cytokines, and Chemokines in Allergic Airway Inflammation, Nicholas W. Lukacs, Robert M. Strieter, and Steven L. Kunkel

Adhesion Molecule Antagonists in Animal Models of Asthma, Roy R. Lobb

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Clinical Medicine
SCIENCE / Life Sciences / Cytology