Advanced MR Neuroimaging: From Theory to Clinical Practice, 1st Edition (Hardback) book cover

Advanced MR Neuroimaging

From Theory to Clinical Practice, 1st Edition

By Ioannis Tsougos

CRC Press

221 pages | 84 Color Illus.

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pub: 2017-12-20
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Over the last decade, some of the greatest achievements in the field of neuroimaging have been related to remarkable advances in magnetic resonance techniques, including diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. Such techniques have provided valuable insights into tissue microstructure, microvasculature, metabolism and brain connectivity.

Previously available mostly in research environments, these techniques are now becoming part of everyday clinical practice in a plethora of clinical MR systems. Nevertheless, despite growing interest and wider acceptance, there remains a lack of a comprehensive body of knowledge on the subject, exploring the intrinsic complexity and physical difficulty of the techniques.

This book focuses on the basic principles and theories of diffusion, perfusion, magnetic resonance spectroscopy, and functional MRI. It also explores their clinical applications and places emphasis on the associated artifacts and pitfalls with a comprehensive and didactic approach.

This book aims to bridge the gap between research applications and clinical practice. It will serve as an educational manual for neuroimaging researchers and radiologists, neurologists, neurosurgeons, and physicists with an interest in advanced MR techniques. It will also be a useful reference text for experienced clinical scientists who wish to optimize their multi-parametric imaging approach.


"I highly recommend Advanced MR Neuroimaging, From Theory to Clinical Practice by Dr Ioannis Tsougos. This book fills a gap in the market at the moment: providing an up-to-date one-stop-shop for the main MR methods most commonly used in clinical practice. It is rare to find a book that covers these techniques in a single text, including how best to use them and their pitfalls, before putting them in the context of a thorough clinical example.

The book can be read at different levels, each chapter providing both an overview of the techniques, in accessible language (with "Focus Point" boxes for quick reference), and also adding depth for those wanting more details. The "Artefacts and Pitfalls of …" chapters are also a welcome addition enabling clinicians and scientists to understand the limitations of the techniques and how to best implement them. The last chapter puts everything in context by providing in-depth and comprehensive coverage of how multimodal neuroimaging could best be used in the assessment of cerebral tumours. I will certainly recommend this book to my colleagues and students as both a perfect introduction to the field, and, at the same time, as a clear and concise way to delve deeper into the MR methods that are now routinely used in the clinic."

Dr Vincent Giampietro, Senior Lecturer and MSc Neuroimaging Programme Leader, King’s College London

"It was a pleasure to read the book Advanced MR Neuroimaging by Dr. Tsougos. Medical imaging, and Magnetic Resonance (MR) in particular, have revolutionized medical care over the past 4 decades in ways unimaginable prior to the introduction of MR. Advanced MR Neuroimaging represents a fundamental tool in understanding brain pathologies and function.

It is no wonder then, that with the critical role MR plays and the rapid innovations in computer technology, that advances in the capabilities and complexity of MR imaging continues to evolve. An up to date complete and authoritative educational and reference volume covering the entire spectrum of advanced MR neuroimaging is a difficult task to accomplish, but the book edited by Dr Tsougos excels in meeting this need.

This book is written by an international author recognized worldwide as a leaders in his field and his extensive experience and practical knowledge is logically presented, well organized and brilliantly visualized. This book consists of comprehensive chapters devoted to all the key areas of advanced MR imaging: Diffusion, Perfusion, Spectroscopy, functional-­-MRI and multi parametric MR Imaging.

Advanced MR Neuroimaging is a comprehensive text and all the chapters are comprehensive. The book is wonderfully well illustrated. I warmly recommend this text to researchers who are interested in a comprehensive introduction to advanced MR neuroimaging."

Professor Luca Saba, Chair of Department of Radiology, Univeristy of Cagliari

"This book is a timely and useful resource for anyone who is interested in advanced magnetic resonance methods as applied to the brain. The approach adopted by the author is very informative and easy to navigate, with chapters devoted to four major techniques (Diffusion, Perfusion, MRS and fMRI), each one immediately followed by an "Artifacts and Pitfalls" chapter with hints and tips on practical implementation. The book is rounded off with a chapter on the assessment of cerebral tumours by multiparametric MR, which ties everything together.

Tsougos’ book will be especially useful for graduate students entering the field, but is of equal relevance to established researchers seeking a "one-stop" overview of current methods."

David J. Lurie, Professor in Biomedical Physics, University of Aberdeen

Table of Contents

Series Preface

Author Bio

1. Diffusion MR Imaging

2. Artifacts and Pitfalls in Diffusion MRI

3. Perfusion MR Imaging

4. Artifacts and Pitfalls of Perfusion MRI

5. Magnetic Resonance Spectroscopy

6. Artifacts and Pitfalls of MRS

7. Functional Magnetic Resonance Imaging (fMRI)

8. Artifacts and Pitfalls off MRI

9. The Role of Multiparametric MR Imaging—Advanced MR Techniques in the Assessment of Cerebral Tumors


About the Author

Dr. Ioannis Tsougos holds a BSc in Physics and an MSc and a PhD in Medical Physics. Currently, he is an Assistant Professor of Medical Radiation Physics at the Medical School of the University of Thessaly, Larissa, Greece and a Visiting Researcher in the Neuroimaging Division at the Institute of Psychiatry, Psychology, & Neuroscience, King’s College London, UK. He has authored more than 70 research papers and 10 international book chapters. He is a member of the EFOMP, ESR, and ESMRMB.

About the Series

Series in Medical Physics and Biomedical Engineering

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Subject Categories

BISAC Subject Codes/Headings:
SCIENCE / Physics
SCIENCE / Life Sciences / Neuroscience