1st Edition

Advances in Biomolecular Medicine Proceedings of the 4th BIBMC (Bandung International Biomolecular Medicine Conference) 2016 and the 2nd ACMM (ASEAN Congress on Medical Biotechnology and Molecular Biosciences), October 4-6, 2016, Bandung, West Java, Indonesia

    Advances in Biomolecular Medicine contains the selected papers presented at the 4th BIBMC (Bandung International Biomolecular Medicine Conference) and the 2nd ACMM (ASEAN Congress on Medical Biotechnology and Molecular Biosciences), hosted by the Faculty of Medicine, Padjadjaran University, Bandung, West Java, Indonesia, 4-6 October 2016. In line with the United Nations Sustainable Development Goals, the theme of the joint scientific meeting is ‘Medical innovation & translational research to ensure healthy lives & promote well-being for all at all ages’.

    Authors include scientists, academics, practitioners, regulators and other key individuals with expertise and experience relevant to biomolecular medicine, medical biotechnology and molecular biosciences. Topics of the papers cover various aspects of infection, oncology, tuberculosis, genetics, thalassemia, nutrition, cardiovascular, wound healing and endocrinology. This book is essential reading for academics, scientist, practitioners and regulators involved in the area of biomolecular medicine, medical biotechnology and molecular biosciences.

    Iron overload intolerance in Balb/c mice
    N. Anggraeni, M.R.A.A. Syamsunarno, R.D. Triatin, D.A. Setiawati, A.B. Rakhimullah, C.C. Dian Irianti, S. Robianto, F.A. Damara, D. Dhianawaty & R. Panigoro

    Mapping of health care facilities in the universal coverage era at Bandung District, Indonesia
    N. Arisanti, E.P. Setiawati, I.F.D. Arya & R. Panigoro

    Influence of phosphatidylcholine on the activity of SHMT in hypercholesterolemic rats
    A. Dahlan, H. Heryaman, J.B. Dewanto, F.A. Damara, F. Harianja & N. Sutadipura

    Molecular detection of DHA-1 AmpC beta-lactamase gene in Enterobacteriaceae clinical isolates in Indonesia
    B. Diela, S. Sudigdoadi, A.I. Cahyadi, B.A.P. Wilopo, I.M.W. Dewi & C.B. Kartasasmita

    Correlation between natrium iodide symporter and c-fos expressions in breast cancer cell lines
    A. Elliyanti, N. Noormartany, J.S. Masjhur, Y. Sribudiani, A.M. Maskoen & T.H. Achmad

    Fat mass profile in early adolescence: Influence of nutritional parameters and rs9939609 FTO polymorphism
    S.N. Fatimah, A. Purba, K. Roesmil, G.I. Nugraha & A.M. Maskoen

    A study of the palatal rugae pattern as a bioindicator for forensic identification among Sundanese and Malaysian Tamils
    R. Khaerunnisa, M. Darjan & I.S. Hardjadinata

    Effect of acrylamide in steeping robusta coffee (Coffea canephora var. robusta) on memory function and histopathological changes of brain cells in male rats (Rattus norvegicus)
    D.Y. Lestari, M. Bahrudin, Rahayu, Fadhil & A.W. A’ini

    Effects of aerobic exercise and a high-carbohydrate diet on RBP4 expression in rat skeletal muscle
    N. Najmi, Y. Sribudiani, B.S. Hernowo, H. Goenawan, Setiawan, V.M. Tarawan & R. Lesmana

    Correlation of physical activity and energy balance with physical fitness among the professors of the University of Padjadjaran
    J. Ninda, L. Lubis, A. Purba, I.B. Akbar, W. Karhiwikarta, Setiawan, V.M. Tarawan, R. Farenia, G.I. Nugraha, M. Rizky Akbar, D.K. Sunjaya, S. Rachmayati, I. Ruslina, Hanna, T. Hidayat, P. Tessa, N. Sylviana, Ronny, T. Nurhayati, Y.S. Pratiwi, N.V. Utami, Juliati, S.N. Fatimah, Y. Indah & F. Huda

    Molecular biology of irreversible pulpitis: A case report
    D. Prisinda & A. Muryani

    Effect of different doses of X-ray irradiation on survival of human esophageal cells
    I.M. Puspitasari, R. Abdulah, M.R.A.A. Syamsunarno & H. Koyama

    The effect of mesenchymal stem cells on the endothelial cells of diabetic mice
    A. Putra, A. Rahmalita, Y. Tarra, D.H. Prihananti, S.H. Hutama & N.A.C. Sa’diyah

    Effects of selenium on SePP and Apo B-100 Gene expressions in human primary hepatocytes
    M. Putri, N. Sutadipura, S. Achmad, C. Yamazaki, S. Kameo, H. Koyama, M.R.A.A. Syamsunarno, T. Iso & M. Kurabayashi

    Inhibition of cAMP synthesis abolishes the impact of curcumin administration in the skeletal muscle of rodents
    H.R.D. Ray & K. Masuda

    Effect of Monosodium Glutamate (MSG) on spatial memory in rats (Rattus norvegicus)
    R. Razali, S. Redjeki & A.A. Jusuf

    Mycobacterium tuberculosis load and rifampicin concentration as risk factors of sputum conversion failure
    E. Rohmawaty, H.S. Sastramihardja, R. Ruslami & M.N. Shahib

    Interleukin-22 serum in comedonal acne vulgaris: Proof of inflammation
    K. Ruchiatan, R. Hindritiani, E. Sutedja & S. Maulinda

    Pharmacokinetic optimization of the treatment of TB meningitis with TB drugs
    R. Ruslami

    Iron-chelating effect of Caesalpinia sappan extract under conditions of iron overload
    R. Safitri, D. Malini, A.M. Maskoen, L. Reniarti, M.R.A.A. Syamsunarno & R. Panigoro

    The role of S.aureus and L.plantarum as an immunomodulator of IFNα macrophages and fibronectin dermal fibroblast secretion
    R.S.P. Saktiadi, S. Sudigdoadi, T.H. Madjid, E. Sutedja, R.D. Juansah, T.P. Wikayani, N. Qomarilla & T.Y. Siswanti

    Exon globin mutation of β-thalassemia in Indonesian ethnic groups: A bioinformatics approach
    N.I. Sumantri, D. Setiawan & A. Sazali

    Serum immunoglobulin-E level correlates with the severity of atopic dermatitis
    O. Suwarsa, E. Avriyanti & H. Gunawan

    Fatty liver in fasted FABP4/5 null mice is not followed by liver function deterioration
    M.R.A.A. Syamsunarno, M. Ghozali, G.I. Nugraha, R. Panigoro, T. Iso, M. Putri & M. Kurabayashi

    The potential of seluang fish (Rasbora spp.) to prevent stunting: The effect on the bone growth of Rattus norvegicus
    Triawanti, A. Yunanto & D.D. Sanyoto

    Effect of cryoprotectants on sperm vitrification
    R. Widyastuti, R. Lesmana, A. Boediono & S.H. Sumarsono

    Mucoprotective effect of Trigona propolis against hemorrhagic lesions induced by ethanol 99.5% in the rat’s stomach
    V. Yunivita & C.D. Nagarajan

    Biography

    Prof. Robert Hofstra studied biology and received a PhD in the medical faculty at the University of Groningen in 1995 for his studies on the involvement of the RET gene in the cancer syndrome MEN2. He worked in the laboratories of Prof. Romeo (Genoa, Italy) to map and characterize the RET gene. After a short postdoctoral appointment he became head of the DNA diagnostic laboratory in 1996 at the Department of Medical Genetics of the UMC Groningen. In 2000 he became head of the Research and Development group at the Department of Medical Genetics, and in 2005 he was appointed as professor of Human Developmental Genetics. In 2012 he accepted an appointment as chair of the Department of Clinical Genetics at the Erasmus MC. His main research objectives over the years were, and still are, to identify and characterize genes and mutations in genes contributing to inherited diseases and cancer and to understand how these mutant genes contribute to disease development. Most of the work in his group is focused on Hirschsprung Disease and Congenital Short Bowel Syndrome.

    Prof. Noriyuki Koibuchi obtained his M.D. and Ph.D, at Gunma University, Japan. He worked as a postdoctoral fellow in the Department of Neurobiology and Behavior at Rockefeller University, and became the Assistant Professor of Physiology at Dokkyo University School of Medicine, Japan. He became a Visiting Assistant Professor of Medicine in the Division of Genetics at Brigham and Women’s Hospital and Harvard Medical School and was appointed to be Professor and Director for the Department of Integrative Physiology at Gunma University Graduate School of Medicine. Dr. Koibuchi’s area of expertise and main interest concern the molecular mechanisms of thyroid hormone action in the central nervous system. He is a member of the Endocrine Society, Society for Neuroscience, and Society of Toxicology.

    Prof. Suthat Fucharoen is a professor at the Institute of Science and Technology for Research and Development, Mahidol University, Thailand. He has conducting research on thalassemia for many years, and his findings provide insights into different types of genetic abnormality that lead to thalassemia in Thai population. He also developed methods in diagnosis of fetal abnormality, which could be carried out through diagnosis of genetic abnormality during the antenatal care. It became a novel approach to control and prevent newborn thalassemic patient in Thailand. Suthat also studied the interaction of genetic defect and the different degree of disease severity, and the pathophysiology of iron deficiency as well as the benefits of using iron chelating agents. He collaborated with both domestic and foreign organizations in creating the thalassemia research network.