1st Edition

Alcohol in Health and Disease



ISBN 9780824705336
Published June 1, 2001 by CRC Press
648 Pages

USD $220.00

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Book Description

This volume, based on presentations from the symposium on the health effects of alcohol held in Titisee, Germany, examines the physical and psychological consequences of alcohol use and abuse, and considers environmental and ethnic factors that lead to addiction and dependence.
Discusses epidemiological studies that show the influence of light to moderate intake of alcoholic beverages on coronary heart disease!
Featuring contributions from nearly 60 internationally recognized and respected authors, and over 2900 references for further investigation of the subject, Alcohol in Health and Disease

  • analyzes biochemical, pharmacogenetic, and pathologic disturbances that follow acute and chronic ingestion of alcohol
  • describes complications that arise from social, biological, and environmental factors
  • examines alcohol metabolic genes and their role in alcohol sensitivity, drinking habits, and dependence
  • spotlights hepatic and nutritional disorders associated with alcoholism
  • considers the relationship of alcohol to cancer
  • debates the French paradox
  • and more!
    Covering a multitude of disciplines, including molecular biochemistry, genetics, epidemiology, pathophysiology, neurobiology, and cardiology, Alcohol in Health and Disease is a critical reference for addiction psychiatrists, neuropsychopharmacologists, psychologists, geneticists, toxicologists, biochemists, environmental and public health scientists, health policy makers, social workers, counselors, and graduate and medical school students in these disciplines.
  • Table of Contents

    Alcohol Metabolism, Alcohol Sensitivity, and Alcoholism

    Functional Polymorphism of Alcohol and Aldehyde Dehydrogenases: Alcohol Metabolism, Alcoholism, and Alcohol-Induced Organ Damage
    Shih-Jiun Yin and Dharam P. Agarwal
    Genes for Alcohol Metabolism and Alcohol Sensitivity: Their Role in the Genetics of Alcohol Dependence
    John B. Whitfield
    Pharmacogenetic Relevance of Aldehyde Dehydrogenases
    Dharam P. Agarwal
    Alcohol Metabolism by Gut Flora: Metabolic, Pathogenetic, and Clinical Implications
    Mikko Salaspuro
    Distribution of Alcohol Dehydrogenase in Human Organs: Relevance for Alcohol Metabolism and Pathology
    Xavier Parés, Susana E. Martínez, Abdellah Allali-Hassani, Emma Borràs, Jaume Farrés,Sílvia Martras, Albert Rosell, and Julia Vaglenova

    Genetic Aspects of Alcohol Use and Dependence

    Genetics and Alcoholism: The COGA Project
    Victor M. Hesselbrock, Tatiana Foroud, Howard Edenberg, John I. Nurnberger, Jr., Theodore Reich, and John P. Rice
    The Genetic Epidemiology of Alcoholism: Sex Differences and Future Directions
    Carol A. Prescott
    The Dopamine D2 Receptor Gene and Alcoholism: Association Studies
    Ulrich Finckh
    Biological Markers of Alcohol Use and Abuse in Theory and Practice
    Anders Helander

    General Health Issues Related to Alcohol Consumption

    Neurobiology of Alcoholism: Recent Findings and Possible Implications for Treatment
    Michael Soyka and Christian G. Schütz
    Neurodegeneration and Neuroadaptation in Alcoholism
    Andreas Heinz and Karl Mann
    Pathogenic Mechanisms in Alcoholic Myopathy
    Victor R. Preedy, Junko Adachi, Sohail Ahmed, David Mantle, Onni Niemela, Seppo Parkkila, Simon Worrall, and Timothy John Peters
    The Alcoholic Patient in the Perioperative Period
    Tim Neumann, Michael Martin, and Claudia Spies
    Alcohol and the Energy Balance: Is Alcohol a Risk Factor for Obesity?
    Paolo M. Suter
    Recent Advances in Fetal Alcohol Syndrome and Alcohol Use in Pregnancy
    Ann P. Streissguth
    Quality of Life in Alcohol-Misusing Subjects
    Timothy John Peters and John Howard Foster

    Alcoholic Liver Disease

    Hepatic, Metabolic, and Nutritional Disorders of Alcoholism: From Pathogenesis to Therapy
    Charles S. Lieber
    Gut-Derived Bacterial Toxins (Endotoxin) and Alcoholic Liver Disease
    J. Christian Bode, Alexandr Parlesak, and Christiane Bode
    Acetaldehyde and Liver Disease
    Kalle Jokelainen
    The Role of Kupffer Cells in Alcoholic Liver Disease
    Carl M. Oneta
    Retinoids and Alcoholic Liver Disease
    Xiang-Dong Wang
    Treatment of Alcoholic Liver Disease
    Helmut K. Seitz and Tatjana Arslic

    Alcohol and Cancer

    Alcohol and Cancer: The Role of Acetaldehyde
    Nils Homann
    Alcohol and Gastrointestinal Cell Regeneration
    Ulrich A. Simanowski and Helmut K. Seitz
    Alcohol and Cancer of the Aerodigestive Tract
    Hiromasa Ishii, Akira Yokoyama, Katsuya Maruyama, and Shinzo Kato

    Alcohol and Cardiovascular Diseases

    Alcohol and Cardiovascular Diseases
    Arthur L. Klatsky
    Beverage Alcohol Consumption as a Negative Risk Factor for Coronary Heart Disease: Biochemical Mechanisms
    David M. Goldberg and George J. Soleas
    Regulation of the Quantity and Quality of High-Density Lipoproteins by Alcohol: A Review
    Minna L. Hannuksela and Markku J. Savolainen
    Alcohol, Lipoproteins, and the French Paradox
    Michael H. Criqui

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    Reviews

    "
    …a useful and brief summary….a useful reference text.
    "-Society for the Study of Addiction to Alcohol and Other Drugs