Alzheimer's Disease : Cause(s), Diagnosis, Treatment, and Care book cover
1st Edition

Alzheimer's Disease
Cause(s), Diagnosis, Treatment, and Care

ISBN 9780367199852
Published June 4, 2019 by CRC Press
351 Pages

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Book Description

Published in 1996: Alzheimer's disease is characterized by memory disturbances and changes in personality and is associated with aging, although it can occur in people under 65. It is a progressive disease, painful to witness as the patient's health declines. Alzheimer's Disease: Cause(s), Diagnosis, and Care, with its complete and authoritative discussions, will help you understand all facets of this complex disease. This book addresses a broad spectrum of topics ranging from diagnosis, causes, treatment, epidemiology, genetics, risk factors, and care and management. Alzheimer's Disease: Cause(s), Diagnosis, and Care is intended for a diverse audience, including practitioners and students, family members, and everyone who is concerned about this disease.

Table of Contents

1. A Synthesis of Critical Topics in Alzheimer's Disease

Z.S. Khachaturian and T.S. Radebaugh

Overview and Historic Perspectives

2. Current Research on Alzheimer's Disease in an Historical Perspective

R. Katzman

3. A History of the Morphology of Alzheimer's Disease

R.D. Terry


4. Putative Risk Factors for Alzheimer's Disease

R. Mayeux

5. Descriptive Epidemiology of Alzheimer's Disease

D.A. Evans

6. Methods of Screening for Survey Research on Alzheimer's Disease and Related Dementias

B.J. Gurland


7. Differential Diagnosis of Alzheimer's Disease

J.C. Morris

8. Clinical Assessment of Patient with Dementia

S. Gilman

9. The Use of Tests and Instruments in the Evaluation of Patients with Dementia

R.C. Mohs

Biological Markers

10. Heterogeneity of Alzheimer's Disease

A. Heyman

11. The Neuropathology of Alzheimer's Disease: Diagnostic Features and Standardization

S.S. Mirra and W.R. Markesbery

12. Pathology, Neurobiology, and Animal Models of Alzheimer's Disease

J.C. Troncoso, B.J. Crain, S.S. Sisodia, and D.L. Price

13. Neuroimaging Applications for the Study of Alzheimer's Disease

T.F. Budinger


14. Intrinsic Biological Aging as Underlying Pathogenetic Mechanism

G.M. Martin

15. Cerebral Metabolic Impairments

J.P. Blass

16. The Metabolism of Apolipoprotein E and the Alzheimer's Diseases

A.D. Roses

17. Neuroimmune Mechanisms in the Pathogenesis of Alzheimer's Disease

P.L. McGeer and E.G. McGeer

18. Causes of Alzheimer's Disease

A.B. Young

19. Trace Elements in Alzheimer's Disease

W.R. Markesbery


20. Clinical Drug Trials in Alzheimer's Disease: Methodological Considerations

L.J. Thal

21. Pharmacological Approaches to Behavioral Symptoms in Alzheimer's Disease

D. Galasko

22. Treatment of Alzheimer's Disease

L. Shihabuddin and K.L. Davis

23. Psychosocial Interventions

M.S. Mittelman and S.H. Ferris

Care and Management

24. Inappropriate Behavior

J. Cohen-Mansfield

25. Managing Problems in Dementia Patients: Depression and Agitation

L. Teri

26. Overview of Psychosocial Factors Contributing to Stress of Family Caregivers

K.C. Buckwalter

27. The Influence of Social Context on the Caregiving Experience

R.J.V. Montgomery

28. Care for Families Facing Alzheimer's Disease: Primary Care Practice Implications from Research

L.P. Gwyther

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Zaven Khachaturian, Ph.D., is co-founder of Khachaturian, Radebaugh & Associates, Inc, an international consulting group focused on the conceptualization, development, and management  of large scale research programs in Alzheimer's disease.

Teresa Sluss Radebaugh, Sc.D., is a psychiatrist epidmiologist with a long history of research and research support work in dementias, Alzheimer's disease and gerontology.