Since the original description of antibodies to endothelial cells in the early 1970s, and with the advent of sensitive and reproducible techniques for their detection, the scope for investigating the vascular damage of immunological disorders has widened considerably. In this book, leading world scientists have contributed chapters presenting broad coverage of basic science and clinical implications of immunological interactions of antibodies to endothelial cells. The book takes a multidisciplinary approach that will appeal to immunologists, rheumatologists, internists, and others interested in the subject.
Immunological Characteristics of the Endothelial Cells: Antibodies to Endothelial Cells: New Clues for the Study of Vascular Damage in the Autoimmune Diseases (A. Palacios-Boix and D. Alarcón-Segovia). Endothelial Cell Biology (J.C. Reverter and J. Monteagudo). Role of Endothelial Cells in the Pathogenesis of Vascular Damage (K.A. Brown). Immunologic Properties of Antibodies to Endothelial Cells: Relationship with Antiphospholipid Antibodies (K.R. McCrae and D.B. Cines). Methods for the Detection of Antibodies to Endothelial Cells (J.M. van der Zee, M.R. Daha and F.C. Breedveld). Antibodies to Endothelial Cells and Vascular Damage in Autoimmune Disorders: Antibodies to Endothelial Cells in Systemic Lupus Erythematosus and Sjögren's Syndrome (D. D'Cruz, A. Jedryka-Góral, and G.R.V. Hughes). Antibodies to Endothelial Cells and Vascular Damage in Rheumatoid Arthritis and Dermatomyositis (R. Cervera, J. Font, and M.A. Khamashta)., Antibodies to Endothelial Cells and Vascular Dysfunction in Progressive Systemic Sclerosis and Mixed Connective Tissue Disease (J.D. Pearson). Antibodies to Endothelial Cells In Systemic Vasculitis (P.L. Meroni, N. Del Papa, G. Conforti, W. Barcellini, M.O. Borghi, and D. Gambini). Antibodies to Endothelial Cells in Renal Diseases and Renal Transplantation (G. Frampton, G.J. Perry, and J.S. Cameron). Antibodies to Endothelial Cells and Vascular Involvement in Multiple Sclerosis (J. Montalbán, M. del Mar Tintoré, and A. Codina). Antibodies to Endothelial Cells in Other Autoimmune Diseases (M. Navarro and A. López-Soto). Index.