Antifungal Therapy: 1st Edition (Paperback) book cover

Antifungal Therapy

1st Edition

Edited by Mahmoud Ghannoum, John R. Perfect, MD

CRC Press

488 pages | 150 B/W Illus.

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Paperback: 9781138114289
pub: 2017-06-07
Hardback: 9780849387876
pub: 2009-11-24
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pub: 2016-04-19
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A concise one-stop-practical reference for the various physicians dealing with fungal infections, Antifungal Therapy appeals to infectious disease physicians, transplant surgeons, dermatologists, and intensivists, as well as basic scientists and pharmaceutical company researchers interested in the state of antifungal therapy.

This book provides a comprehensive, up-to-date overview of the pertinent issues pertaining to antifungal treatment. Divided into four interrelated sections for a cohesive discussion covers:

  • history of antifungals from the discovery of the polyenes to the echinocandins
  • antifungal susceptibility methods
  • patient management
  • animal models in drug development
  • therapeutic strategies
  • pharmacokinetic and pharmacogenomics
  • trends in resistance

Table of Contents

General Introduction to the Management Issues

History of Antifungals

Ali Abdul Lattif and Kim Swindell

Epidemiology of Fungal Infections: What, Where, and When

Sylvia F. Costa and Barbara D. Alexander

Experimental Animal Models of Invasive Fungal Infections

Yoshifumi Imamura and Mahmoud A. Ghannoum

Antifungal Drug Resistance: Significance and Mechanisms

Pranab K. Mukherjee and Mingyue Wang

Antifungal Prophylaxis: An Ounce of Prevention isWorth a Pound of Cure

Aimee K. Zaas

Preemptive Antifungal Therapy: Do Diagnostics Help?

Kimberly E. Hanson

The Immune Response to Fungal Challenge

Jeffery J. Auletta

Immunomodulators: What is the Evidence for Use in Mycoses?

J. Andrew Alspaugh

Fungal Biofilms and Catheter-Associated Infections

Jyotsna Chandra and Mahmoud A. Ghannoum

Antifungal Drug Classes

Polyenes for Prevention and Treatment of Invasive Fungal Infections

Richard H. Drew


Richard H. Drew

Pharmacology of Azole Antifungal Agents

Elizabeth S. Dodds Ashley

Echinocandins for Prevention and Treatment of Invasive Fungal Infections

Melissa D. Johnson and John Mohr

Novel Administrations of Antifungals

Richard H. Drew

Management of Specific Mycoses


Susan A. Keiler and Mahmoud A. Ghannoum

Invasive Candidiasis

Rana Traboulsi and Mahmoud A. Ghannoum

Invasive Aspergillosis

Rana Traboulsi

Management of Cryptococcosis

John R. Perfect

Management of Endemic Mycoses

John R. Perfect

Human Hyalohyphomycoses: A Review of Human Infections Due to Acremonium spp., Paecilomyces spp., Penicillium spp., and Scopulariopsis spp.

Mahmoud A. Ghannoum

Management of Phaeohyphomycosis

John R. Perfect


Kim Swindell

Management of Zygomycosis

John R. Perfect

The Paradigm of Risk Group/Infection Site Assessments

Antifungal Management in Risk Groups: Transplant Recipients

Sylvia F. Costa and Barbara D. Alexander

Prophylaxis and Treatment of Invasive Fungal Infections in Neutropenic Cancer and Hematopoietic Stem Cell Transplant Patients

Selmin A. Ataergin and Hillard M. Lazarus

Infants: Yeasts Are Beasts in Early Life

P. Brian Smith and Daniel K. Benjamin, Jr.

Newer Antifungal Agents in Pediatrics

Christina Henn and William J. Steinbach

Fungal Infections in Burn Patients

Jose A. Vazquez

Allergic Bronchopulmonary Aspergillosis

Rana Traboulsi

Fungal Infections of the Genitourinary Tract

Rana Traboulsi and Souha Kanj

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Critical Care
MEDICAL / Dermatology
MEDICAL / Infectious Diseases