1st Edition

Applications in Plant Biotechnology Focus on Plant Secondary Metabolism and Plant Molecular Pharming

Edited By Abdullah Makhzoum, Kathleen Hefferon Copyright 2023
    364 Pages 10 Color & 12 B/W Illustrations
    by CRC Press

    364 Pages 10 Color & 12 B/W Illustrations
    by CRC Press

    The book focuses on interesting topics in plant biotechnology and its applications. The first section covers a number of specific medicinal plants and their secondary metabolites using genetic and metabolic engineering. The pharmaceutical uses of these plant bioactive compounds and their applications in treating a variety of diseases including cancer, as well as recent works on in silico and bioinformatic analysis are described. The second section deals with innovative plant molecular pharming approaches and reviews the potential for using various plant host systems to design and produce effective new drugs to treat different illnesses and diseases such as HIV, infectious diseases, and other human and livestock diseases.

    Part 1: Plant Secondary Metabolism

    1. Withania somnifera: A Future Pharma Factory

    Tarun Halder, Subrata Kundu and Biswajit Ghosh

    2. Biotechnological Approaches for Tropane Alkaloids Production

    Ryad Amdoun, Boualem Harfi, Asma Moussous, Abdullah Makhzoum and Lakhdar Khelifi

    3. Anticancer Mechanisms of Plant Secondary Metabolism

    David O. Nkwe

    4. In silico and Computational Analysis of Plant Secondary Metabolites from African Medicinal Plants

    Smith B. Babiaka, Pascal Amoa Onguéné, Boris Davy Bekono and Fidele Ntie-Kang

    5. Botany, Phytochemistry, Pharmacology, and Toxicity of the Southern African Strychnos Species

    Willie Marenga, Abdullah Makhzoum and Gaolathe Rantong

    6. Preference of Agrobacterium rhizogenes Mediated Transformation of Angiosperms

    Kamogelo M Mmereke, Aaqib Javid, Sukanya Majumdar, Ipshita Ghosh, Sonia Malik, Abdullah Makhzoum and Sumita Jha

    Part 2: Plant Molecular Pharming

    7. Plant Molecular Pharming: Methods, Tools, Challenges Ahead for Production of Recombinant Proteins, and Potential Solutions

    Shahram Shokrian Hajibehzad, Azadeh Mohseni, Mohammad Dolati, Saeid Malekzadeh Shafaroudi, Kathleen Hefferon and Abdullah Makhzoum

    8. Plant-based Vaccines against Livestock Diseases: Way to Achieve Several Sustainable Development Goals

    Mohammad Tahir Waheed, Muhammad Suleman Malik, Kiran Saba, Iqra Younus, Niaz Ahmad, Bushra Mirza and Andreas Günter Lössl

    9. Chloroplast Biotechnology Tools for Industrial and Clinical Application

     Kwang-Chul Kwon

    10. Plant Virus-Based Expression Vectors and their Applications in Foreign Protein/Antigen Expression

    Srividhya Venkataraman, Erum Shoaeb and Kathleen Hefferon

    11. Plant Molecular Pharming of Biologics to Combat HIV

    Goabaone Gaobotse, Jocelyne Trémouillaux-Guiller, Srividhya Venkataraman, Mohammed Kamil Sherif, Abdullah Makhzoum and Kathleen Hefferon


    Professor Abdullah Makhzoum received his PhD from the University of Tours in France, and completed his postdoctoral fellowship as well visitor Scientist at Western University in Ontario, Canada. Abdullah has published numerous research papers, chapters and reviews, and he is now working as an associate professor in the department of Biological Sciences and Biotechnology at BIUST University. His research interests include most aspects of plant biotechnology and its applications such as plant secondary metabolites, plant molecular pharming, phytoremediation and Plant Bioinformatics.

    Professor Kathleen Hefferon received her PhD from the Department of Medical Biophysics, University of Toronto and completed a postdoctoral fellowship at Cornell University. Kathleen has published several research papers, chapters and reviews, and has written three books. Kathleen is the Fulbright Canada Research Chair of Global Food Security and has been a visiting professor at the University of Toronto over the past year. Her research interests include virus expression vectors, food security agricultural biotechnology and global health. Kathleen lives in New York with her husband and two children.