1st Edition

Artificial Neural Networks in Cancer Diagnosis, Prognosis, and Patient Management

Edited By R. N. G. Naguib, G. V. Sherbet Copyright 2001
    216 Pages
    by CRC Press

    214 Pages
    by CRC Press

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    The potential value of artificial neural networks (ANN) as a predictor of malignancy has begun to receive increased recognition. Research and case studies can be found scattered throughout a multitude of journals. Artificial Neural Networks in Cancer Diagnosis, Prognosis, and Patient Management brings together the work of top researchers - primarily clinicians - who present the results of their state-of-the-art work with ANNs as applied to nearly all major areas of cancer for diagnosis, prognosis, and management of the disease.

    The book introduces the theory of neural networks and the method of their application in oncology. It is not an exercise in ANN research, but the presentation of a new technique for diagnosing and determining the treatment of cancers. The authors have included almost all cancers for which there exist ANN applications. When the data available is ill-defined and the development of an algorithmic solution difficult, neural networks provide a non-linear approach which helps sift through the maze of information and arrive at a reasonable solution.

    Highly interdisciplinary in nature, this book provides comprehensive coverage of the most important materials relating to the applications of ANNs in the cancer field. With contributions from prominent research centers worldwide, it serves as an introduction to how neural networks can be used for accurate prediction or diagnosis and shows why neural networks are more accurate. Artificial Neural Networks in Cancer Diagnosis, Prognosis, and Patient Management gives you an understanding of this new tool, its applications, and when it should be used.

    Introduction to Artificial Networks and Their Use in Cancer Diagnosis, Prognosis, and Patient Management. Analysis of Molecular Prognostic Factors in Breast Cancer by Artificial Neural Networks. Artificial Neural Approach to Analysing the Prognostic Significance of DNA Ploidy and Cell Cycle Distribution of Breast Cancer Aspirate Cells. Neural Networks for the Estimation of Prognosis in Lung Cancer. The Use of a Genetic Algorithm Neural Network (GANN) for Prognosis in Surgically Treated Non-Small Cell Lung Cancer (NSCLC). The Use of Machine Learning in Screening for Oral Cancer. Outcome Prediction of Oesophago-Gastric Cancer Using Neural Analysis of Pre- and Post-Operative Parameters. Artificial Neural Networks in Urologic Oncology. Neural Networks in Urologic Oncology. Comparison of a Neural Network with High Sensitivity and Specificity to Free/Total Serum PSA for Diagnosing Prostate Cancer in Men with PSA. Artificial Neural Networks and Prognosis in Prostate Cancer. Comparison Between Urologists and Artificial Neural Networks in Bladder Cancer Outcome Prediction. A Probabilistic Neural Network Framework for Detection of Malignant Melanoma.


    Raouf Naguib, Ph.D., is Professor of Biomedical Computing in the School of Mathematical and Information Sciences, Coventry University, England, where he also leads the Biomedical Computing Research Group. Prior to this appointment, he was a Lecturer at the University of Newcastle upon Tyne, England. Professor Naguib received the degrees of Ph.D., M.Sc. (with distinction), and D.I.C. from Imperial College of Science, Technology and Medicine, University of London, England, and the B.Sc. degree from Cairo University, Egypt. In 1995–1996 he was awarded the Fulbright Cancer Fellowship to pursue his research at the University of Hawaii in Mãnoa on the applications of artificial neural networks in breast cancer diagnosis and prognosis. Professor Naguib is a Chartered Engineer and a member of the Institution of Electrical Engineers (IEE), the Institute of Physics and Engineering in Medicine (IPEM), the American Association for Cancer Research (AACR), and a Senior Member of the Institute of Electrical and Electronics Engineers (IEEE). He is the representative of IEEE Engineering in Medicine and Biology Society (EMBS) to the European Society for Engineering and Medicine, and the IEEE-USA Committee on Communications and Information Policy. He is also a Special Area Editor for the IEEE Transactions on Information Technology in Biomedicine. Professor Naguib has worked extensively on the applications of artificial neural networks in the field of clinical oncology. This work was also combined with studies on image processing, image cytometry and the stratification of significant conventional and experimental prognostic markers in a variety of cancers. His current interests lie in the applications of evolutionary computational models, fuzzy logic, genetic algorithms and parallel image processing methodologies to cancer diagnosis, prognosis and disease management. He also has a special interest in content-based image retrieval and human form perception for histopathological identifi