Published in 1995: Aspartic Proteinases: Physiology and Pathology focuses on the advantages and limitations of the use of proteinases and their inhibitors in human pathology. A virus-specific aspartic proteinase enzyme is required for the maturation of a virus. If the enzyme can be eliminated, so can the maturation of the virus. This book reviews the wealth of recently published information sparked by the renewed interest in these enzymes.
Table of Contents
1. Introduction 2. Apartic Proteinases – an Overview 3. Pepsin A and Gastricsin and their Zymogens 4. Renin 5. Cathepsin D 6. Cathepsin E 7. Aspartic proteinases of Candida Yeasts 8. Aspartic Proteinase of Plasmodium falciparum 9. HIV and Retroviral Proteinases
Martin Fusek, Ph.D. is a member of the Department of Biochemistry of the Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences in Prague, Czech Republic.
Vaclac Vetvicka, Ph.D. is an Assistant Professor at the Department of Pathology, Division of Experimental Immunology and Immunopathology of the School of Medicine, University of Lousiville, Louisville, Kentucky.