Astrocytes play diverse roles in central nervous system (CNS) function and dysfunction, and the connections that the astrocyte makes with other cells of the brain are essential for a variety of important neural tasks. Bringing together contributions from international experts at the top of their field, Astrocytes: Wiring the Brain emphasizes cellul
Introduction to Cluster A: Functional Biomarkers at the Interface. Mature Protoplasmic Mammalian Astrocytes: Morphology, Interrelationships, and Implications for Function. Biomarkers of Astrocyte Microdomains: Focus on Gap Junctions, Purinergic Receptors, and Aquaporins. Adhesion Molecules and their Function in Astrocyte Polarity. Contribution of Astrocytes to CNS Immunity: Roles of Pattern Recognition Receptors (PRRs). Introduction to Cluster B: Establishment of Functional Units:Multimodality at the Tips. Neuroglial Networks: Glial Wiring Also Matters. Astrocyte-Neuron Communication: What Goes Wrong in Pathology? Blood-Brain Barrier and the Neural Vascular Unit. Oligodendrocytes: Gateway to the Panglial Syncytium. Microglia and Non-CNS Cells in Paracrine Signaling and CNS Immunity: Effects of Pathogens, Age, and Life History. CNS Pathology: Disruption of Astrocyte Connectivity: Introduction. Astrocytes in Epilepsy. Astrocyte Involvement in the Acquired Demyelinating. The Role of Glial Pathology in Autism. Astrocytes in Major Depressive Disorder and Schizophrenia: Pathophysiological and Therapeutic Aspects. Index.