This comprehensive book describes in detail the most topical emerging areas of scientific importance involving the use of spores and covers their use as probiotics in humans and animals and also with plants. In addition authors present the emerging use of the spore as a tool for nanobiotechnology where the spore can be used for the efficient display of heterologous proteins on the spore surface. The use of this technology and systematics of spore forming bacteria, and the architecture and assembly of spores.
The innovative topics covered in this book will be of particular interest to scientists working in all areas of probiotic research and vaccine technology and is recommended reading for microbiologists involved with Bacillus spp. and other spore forming bacteria.
Table of Contents
Section I. General Aspects. 1. Ubiquity, Longevity, and Ecological Roles of Bacillus Spores. 2.Taxonomy and Systematics of Aerobic Endospore Forming Bacteria. 3. Ecology of Bacillus Species in Soil. 4. Pathogenic Bacilli: B. anthracis and Close Relatives. 5. Sporulation in Bacillus subtilis and other bacteria. 6. The Functional Architecture and Assembly of the Spore Coat. 7. The Spore Surface. Section II. Spores as Probiotics. 8. Safety of Aerobic Endospore-Forming Bacteria. 9. The Fate of Ingested Spores. 10. Mechanisms of Gene Transfer and the Spread of Antibiotic Resistance in Spore Forming Organisms in the GI Tract. 11. Bacillus Spores as Probiotic Products for Human Use. 12. Production and Probiotic Effects of Natto. 13. Spore Probiotics as Animal Feed Supplements. 14. The Potential for Use of Bacillus spp. in Sports Turf Management. 15. Antimicrobial Activity of Bacillus Probiotics. 16. Gut Sporeformers. Section III. Spores as Vaccine Vehicles. 17. Display of Molecules on the Spore Surface. 18. Spores as Oral Vaccines.
The book brings together ecological and molecular approaches in a novel and refreshing way...It also has a commendable emphasis on applications, especially of our molecular genetic knowledge, and looks for these in both the developed and developing worlds...The book has been well edited and is attractively produced - Society for General Microbiology