1st Edition

Bioengineering and Biomaterials in Ventricular Assist Devices

Edited By Eduardo Guy Perpétuo Bock Copyright 2022
    362 Pages 222 B/W Illustrations
    by CRC Press

    Often associated with artificial hearts, ventricular assist devices (VADs) are blood pumps that can provide circulatory assistance to the left ventricle, the right ventricle, or both. Bioengineering and Biomaterials in Ventricular Assist Devices reviews constructive details of VADs and the biomaterials used in their development and support.

    FEATURES

    • Establishes an area of intersection between engineering and medicine
    • Shows process development from mechanical design to automation and control
    • Discusses biofunctional materials, tribology in ceramic biomaterials, biosensors, and surface engineering and blood

    This text is aimed at advanced students, researchers, and practicing engineers conducting work on VADs and will be of interest to a broad interdisciplinary group, including bioengineers, materials engineers, chemical engineers, mechanical engineers, and electrical engineers.

    Part I Bioengineering in Ventricular Assist Devices

    Chapter 1 VAD Design

    Aron J. P. Andrade, Gustavo C. Andrade, Juliana Leme, and Bruno U. Silva

    Chapter 2 Electromechanical Actuators

    Breno Y. T. Nishida and Rogerio L. de Souza

    Chapter 3 Cardiovascular System Simulators

    Jeison Willian Gomes da Fonseca, Breno T. Y. Nishida, and Gustavo C. de Andrade

    Chapter 4 Control Systems

    Bruno Jesus dos Santos and Tarcísio F. Leão

    Chapter 5 Supervisory and Intelligent Systems

    Marcelo Barboza, José Ricardo de Sousa Sobrinho, Jonatas Dias, and Diolino José dos Santos Filho

    Chapter 6 Safety and Security

    André Cavalheiro

    Part II Biomaterials in Ventricular Assist Devices

    Chapter 7 Hemocompatibility, Hemolysis, Cell Viability, and Immunology

    Wesley L. Fotoran

    Chapter 8 Computational Hemodynamics

    Guilherme B. Lopes Jr, Luben Cabezas-Gómez, and Raquel J. Lobosco

    Chapter 9 Biofunctional Materials

    Rosa Corrêa Leoncio de Sá

    Chapter 10 Bioceramics for VADs

    Fernando dos Santos Ortega

    Chapter 11 Tribology in Ceramic Biomaterials

    Rodrigo Lima Stoeterau

    Chapter 12 Surface Engineering of Biomaterials by Plasma Electrolytic Oxidation

    César A. Antônio, Rosana F. Antônio, Elidiane C. Rangel, and Nilson C. Cruz

    Chapter 13 Additive Manufacturing for VADs

    Adriana Del Monaco De Maria and Evandro Drigo

    Chapter 14 Laser Additive Manufacturing for the Realization of New Material Concepts

    Wilhelm Pfleging and Juliana dos Santos Solheid

    Chapter 15 Biosensors

    Bruno Jesus dos Santos and Henrique Stelzer Nogueira

    Chapter 16 Optics and VADs

    Isac K. Fujita and Sergio Y. Araki

    Biography

    Eduardo Guy Perpétuo Bock is Associate Professor and Head of the Laboratory of Bioengineering and Biomaterials at the Department of Mechanics in Federal Institute of São Paulo since 2007. He is Bachelor in Mechanical Engineering by University São Judas Tadeu, Masters and PhD in Mechanical Engineering by State University of Campinas. He worked as Field Engineer in Angel Medical Systems in Shrewsbury, New Jersey; Assistant Professor in FAAP, São Paulo; and Project Intern in Baylor College of Medicine, Houston. He has filed the patent “Implantable equipment for temporary life support of patients waiting for heart transplantation”. In addition, he had published 3 books, 14 chapters and 44 papers in scientific journals with 427 citations. He has experience in the field of Biomedical and Mechanical Engineering, with emphasis on Bioengineering acting mainly on the following themes: Biomaterials, Tribology, Numerical Simulation, Control Systems, Artificial Organs, Artificial Heart, Ventricular Assist Devices and Mechanical Circulatory Support.

    "This edited volume focuses on the engineering and blood-materials interactions in ventricular assist devices (VADs). These are complex marvels of the medical field and a success story of biomedical engineering in the 20th century. All the authors come from academic institutions in Brazil, but the work is general, and interest in it is not limited to this geographical region. A well-organized overview of VADs precedes more-detailed concepts, including actuators, simulation circuits, and control systems. Some autobiographical information related to contributing authors will interest students of the history and social aspects of biomedical science. Informative tables offer quantitative, clinically relevant information on VAD devices. Equations, data graphs, and diagrams are well used, and sparing use of color figures enhances understanding. The biomaterials chapters are less quantitative, by their nature, although they will likely still interest practitioners and students of the field. This is a very well done review and a useful reference: readers are offered an in-depth appreciation of the recent history of this field."

    Summing Up: Highly recommended. Upper-division undergraduates. Graduate students, faculty, and professionals.

    —M. R. King, Vanderbilt University, Choice, October 2022