Biomedical Photonics Handbook: Fundamentals, Devices, and Techniques, 2nd Edition (Hardback) book cover

Biomedical Photonics Handbook

Fundamentals, Devices, and Techniques, 2nd Edition

Edited by Tuan Vo-Dinh

CRC Press

850 pages | 32 Color Illus. | 205 B/W Illus.

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pub: 2014-07-29
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Shaped by Quantum Theory, Technology, and the Genomics Revolution

The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents recent fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The first volume, Fundamentals, Devices, and Techniques, focuses on the fundamentals of biophotonics, optical techniques, and devices.

Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians

Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies.

What’s New in This Edition:

A wide variety of photonic biochemical sensing technologies has already been developed for clinical monitoring of physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics, and metabolomics allow sensing of early disease states, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules, and in situ diagnostics at the single-cell level. In addition to these state-of-the-art advancements, the second edition contains new topics and chapters including:

• Fiber Optic Probe Design

• Laser and Optical Radiation Safety

• Photothermal Detection

• Multidimensional Fluorescence Imaging

• Surface Plasmon Resonance Imaging

• Molecular Contrast Optical Coherence Tomography

• Multiscale Photoacoustics

• Polarized Light for Medical Diagnostics

• Quantitative Diffuse Reflectance Imaging

• Interferometric Light Scattering

• Nonlinear Interferometric Vibrational Imaging

• Multimodality Theranostics Nanoplatforms

• Nanoscintillator-Based Therapy

• SERS Molecular Sentinel Nanoprobes

• Plasmonic Coupling Interference Nanoprobes

Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and lists of references for further reading.

Table of Contents

Photonics and Tissue Optics

Optical Properties of Tissues

Joel Mobley, Tuan Vo-Dinh and Valery Tuchin

Light-Tissue Interactions

Valery V. Tuchin

Theoretical Models and Algorithms in Optical Diffusion Tomography

Stephen J. Norton and Tuan Vo-DinhBasic Instrumentation

Basic Instrumentation in Photonics

Tuan Vo-Dinh

Optical Fibers and Waveguides for Medical Applications

Israel Gannot and Moshe Ben David

Fiberoptics Probe Design

Urs Utzinger

Laser and Optical Radiation Safety in Biophotonics

Robert J. Landry, T. Joshua Pfefer, and Ilko K. IlevPhotonic Detection and Imaging Techniques

Biological Imaging Spectroscopy

Gregory Bearman, David Cuccia and Richard Levenson

Lifetime-Based Imaging

Petr Herman and Joseph R. Lakowicz

Confocal Microscopy

Tony Wilson

Two-Photon Excitation Fluorescence Microscopy

Peter T.C. So, Chen Y. Dong, and Barry R. Masters

Laser Doppler Perfusion Monitoring and Imaging

T. Stromberg and K. Wardell, M. Larsson, and E.G. Salerud

Light Scatter Spectroscopy and Imaging of Cellular and Subcellular Events

Nada N. Boustany and Nitish V. Thakor

Tissue Viability Imaging

Gert E. Nilsson

Photothermal Detection and Tracking of Individual Non-fluorescent Nanosystems

Laurent Cognet & Brahim Lounis

Thermal Imaging

Jay Gore and Lisa X. Xu

Multidimensional fluorescence imaging of biological tissue

Paul French

Speckle Correlometry

Dmitry A. Zimnyakov and Valery V. TuchinSpectroscopic Data

Spectroscopic Data in Biological and Biomedical Analysis

Dimitra N. Stratis-Cullum, Mikella E. Farrell, Ellen Holthoff, David L. Stokes,

Brian M. Cullum, Joon Myong Song, Paul M. Kasili, Ramesh Jaganathan,

and Tuan Vo-Dinh

About the Editor

Tuan Vo-Dinh is the R. Eugene and Susie E. Goodson Distinguished Professor of biomedical engineering, professor of chemistry, and director of the Fitzpatrick Institute for Photonics at Duke University. He received a B.S. in physics in 1970 from EPFL (Ecole Polytechnique Federal de Lausanne) in Lausanne and a Ph.D. in physical chemistry in 1975 from ETH (Swiss Federal Institute of Technology) in Zurich, Switzerland. Dr. Vo-Dinh has authored over 350 publications in peer-reviewed scientific journals. He is the author of a textbook on spectroscopy and editor of 6 books. He has received numerous awards and holds over 37 U.S. and international patents.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
SCIENCE / Physics