Biomedical Photonics Handbook: Therapeutics and Advanced Biophotonics, 2nd Edition (Hardback) book cover

Biomedical Photonics Handbook

Therapeutics and Advanced Biophotonics, 2nd Edition

Edited by Tuan Vo-Dinh

CRC Press

767 pages | 30 Color Illus. | 254 B/W Illus.

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pub: 2014-07-29
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Shaped by Quantum Theory, Technology, and the Genomics Revolution

The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents recent fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The third volume, Therapeutics and Advanced Biophotonics, focuses on therapeutic modalities, advanced biophotonic technologies, and future trends.

Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians

Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies.

What’s New in This Edition:

A wide variety of photonic biochemical sensing technologies has already been developed for clinical monitoring of early disease states and physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics, and metabolomics allow sensing of early disease states, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules and in situ diagnostics at the single-cell level. In addition to these state-of-the-art advancements, the second edition contains new topics and chapters including:

• Fiber Optic Probe Design

• Laser and Optical Radiation Safety

• Photothermal Detection

• Multidimensional Fluorescence Imaging

• Surface Plasmon Resonance Imaging

• Molecular Contrast Optical Coherence Tomography

• Multiscale Photoacoustics

• Polarized Light for Medical Diagnostics

• Quantitative Diffuse Reflectance Imaging

• Interferometric Light Scattering

• Nonlinear Interferometric Vibrational Imaging

• Nanoscintillator-Based Therapy

• SERS Molecular Sentinel Nanoprobes

• Plasmonic Coupling Interference Nanoprobes

Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and a list of references for further reading.

Table of Contents

Therapeutic and Interventional Techniques

Mechanistic Principles of Photodynamic Therapy

Barbara W Henderson Sandra O Gollnick

Synthesis and Biological Significance of Porphyrin-based Photosensitizers in Photodynamic Therapy

Penny Joshi Ravindra K Pandey

Lasers in Dermatology

Lilit Garibyan H Ray Jalian Kittisak Suthamjariya and R Rox Anderson

Lasers in Interventional Pulmonology

Anubhav N Mathur Praveen N Mathur

Lasers in Diagnostics and Treatment of Brain Diseases

Steen J Madsen Bernard Choi Henry Hirschberg

Lasers in Ophthalmology

Ezra Maguen Thomas G Chu and David Boyer

Lasers in Otolaryngology

Lou Reinisch

Therapeutic Applications of Lasers in Gastroenterology

Masoud Panjehpour Bergein F Overholt

Low-Power Laser Therapy

Tina I Karu

Image Guided Surgery

Richard D Bucholz Keith A Laycock

Optical Methods for Caries Detection Diagnosis and Therapeutic Intervention

Daniel Fried

Nonlinear Interferometric Vibrational Imaging and Spectroscopy

Haohua Tu Zhi Jiang Praveen D Chowdary Wladimir Benalcazar Eric J Chaney Daniel L Marks Martin Gruebele Stephen A Boppart

Multifunctional Theranostic Platform: Plasmonic-Active Gold Nanostars

Hsiangkuo Yuan, Andrew M Fales, Tuan Vo-Dinh

Activity of psoralen-functionalized nanoscintillators against cancer cells upon X-ray excitation

John Scaffidi Molly K Gregas Bernard Lauly Yang Zhang Tuan Vo-DinhAdvanced Biophotonics and Nanophotonics

Living Cell Analysis Using Optical Methods

Pierre M Viallet Tuan Vo-Dinh

Amplification Techniques for Optical Detection

Guy D Griffin Dimitra N Stratis-Cullum Timothy E McKnight M Wendy Williams Tuan Vo-Dinh

Fluorescent Probes in Biomedical Applications

Darryl J Bornhop Kai Licha and Lynn E Samuelson

Optical Trapping Techniques in Bioanalysis

Kenji Yasuda

Luminescent Nanoparticle-Based Probes for Bioassays

Georgeta Crivat Sandra M Da Silva Ashley D Quach Venkata R Kethineedi Matthew A Tarr and Zeev Rosenzweig

Fluorescent Molecular Beacon Nucleic Acid Probes for Biomolecular Recognition

Cuichen Wu Chaoyong James Yang Kemin Wang Xiaohong Fang Terry Beck Richard Hogrefe Weihong Tan

Luminescent Quantum Dots for Diagnositc and Bioimaging Applications

Brad A Kairdolf Shuming Nie

PEBBLE nanosensors for in vitro bioanalysis

Yong-Eun Koo Lee Eric Monson Murphy Brasuel Martin A Philbert Raoul Kopelman

Nanosensors for Single-Cell Analyses

Charles K Klutse Brian M Cullum, Molly K Gregas, John P Scaffidi, Tuan Vo-Dinh

SERS Molecular Sentinel Nanoprobes to Detect Biomarkers for Medical Diagnostics

Tuan Vo-Dinh Hsin-Neng Wang Hoan Thanh Ngo

Plasmonic Coupling Interference (PCI) Nanoprobes for Gene Diagnostics

Hsin-Neng Wang Stephen Norton Tuan Vo-Dinh

DNA Sequencing using Fluorescence Detection

Steven A Soper Clyde V Owens Suzanne J Lassiter Yichuan Xu and Emanuel Waddell

In Vivo Bioluminescence Imaging as a Tool for Drug Development

Pamela R Contag Christopher H Contag

About the Editor

Tuan Vo-Dinh is the R. Eugene and Susie E. Goodson Distinguished Professor of biomedical engineering, professor of chemistry, and director of the Fitzpatrick Institute for Photonics at Duke University. He received a B.S. in physics in 1970 from EPFL (Ecole Polytechnique Federal de Lausanne) in Lausanne and a Ph.D. in physical chemistry in 1975 from ETH (Swiss Federal Institute of Technology) in Zurich, Switzerland. Dr. Vo-Dinh has authored over 350 publications in peer-reviewed scientific journals. He is the author of a textbook on spectroscopy and editor of 6 books. He has received numerous awards and holds over 37 U.S. and international patents.

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biotechnology
SCIENCE / Physics