Biotechnology in the Modern Medicinal System: Advances in Gene Therapy, Immunotherapy, and Targeted Drug Delivery presents an informative picture of the state-of-the-art research and development of actionable knowledge in medical biotechnology, specifically involving gene therapy, immunotherapy, and targeted drug delivery systems. The book includes novel approaches for therapy of various ailments and the real-world challenges and complexities of the current drug delivery methodologies and techniques.
The volume helps to bridge the gap between academic research and real-time clinical applications and the needs of medical biotechnology methods. This edited book also provides a detailed application of medical biotechnology in drug discovery and the treatment of various deadly diseases.
Chapters discuss targeted drug delivery to specific sites to avoid possible entry to non-targeted sites, minimizing adverse effects. The volume provides information about the roles of alternative routes of drug targeting, like intranasal and transdermal, resulting in improving patient compliance. Targeted drug delivery is explored for several health issues, such as neurodegenerative disorders, cancer, malaria, and hemoglobin disorders. Also considered is the role of genes in various genetic diseases and gene therapy, and immunogene therapy as alternative approaches to conventional cancer therapy.
Finally, the book investigates the important role of computers in biotechnology to accelerate research and development in the modern medicinal field for better and optimum results. Studies show that significant improvement has been observed in the development of a faster and less invasive diagnostic system for the treatment of diseases by utilizing both artificial intelligence (AI) and biotechnology.
This valuable volume provides a wealth of information that will be valuable to scientists and researchers, faculty, and students.
Table of Contents
1. Role of Naturally Occurring Lead Compounds as Potential Drug Targets against Malaria
Neha Kapoor and Soma M. Ghorai
2. Targeted Drug Delivery
Princy Choudhary and Sangeeta Singh
3. Targeted Delivery of Biopharmaceuticals for Neurodegenerative Disorders
Sarika Wairkar and Vandana Patravale
4. Genes in Genetic Disease
Sukanya Bhoumik and Syed Ibrahim Rizvi
5. Current Perspectives and Trends in Gene Therapy and Their Clinical Trials
Pramod Kumar Maurya, Neha Shree Maurya, and Ashutosh Mani
6. Immunogene Therapy in Cancer
Sreeranjini Pulakkat and Vandana Patravale
7. Gene Therapy for Hemoglobin Disorders
Sora Yasri and Viroj Wiwanitkit
8. Artificial Intelligence and Biotechnology: The Golden Age of Medical Research
Upendra Kumar and Kapil Kumar Gupta
Rajesh K. Kesharwani, PhD, is Associate Professor in the Department of Computer Application, Nehru Gram Bharati (Deemed to be University), Prayagraj, Uttar Pradesh, India. He has received several awards, including the NASI-Swarna Jayanti Puruskar from The National Academy of Sciences of India. He has supervised PhD, postgraduate, and undergraduate students for their research work and has authored over 40 peer-reviewed articles, more than 20 book chapters, and over 10 edited books with international publishers. He is a member of many scientific communities as well as a reviewer for many international journals and has presented many papers at various national and international conferences.
Krishna Mishra, PhD, is superannuated as Professor of Chemistry at the University of Allahabad, India, where she occupied the Chair of the Biochemistry Department and was the first coordinator of the Center for Biotechnology. She is also a senior scientist and fellow of the National Academy of Sciences, India, where she was formerly General Secretary. In addition, she is Chief Advisor for India Pesticides Ltd., Lucknow, and was a member of the advisory board of Biotech Park, Lucknow. She was awarded a NASI Platinum Jubilee Senior Scientist Fellowship. Dr. Mishra is Chairperson of the STEM program of the Department of Science and Technology and Chemistry Advisory Board of Uttar Pradesh Council of Science and Technology. She was an expert on many selection committees and is also on the editorial boards of many national and international journals. She has published several books, about 20 reviews, a dozen book chapters, and many papers at national and international conferences and also holds several patents in US and India.
"Provides a wealth of information that will be valuable to scientists, researchers, faculty, and students in the field of biomedical sciences. All the contributing authors demonstrate an exceptional expertise in the field of medicinal biotechnology research and development, and provide a global perspective on current and future advances in new drug discovery. This volume provides detailed information on the application of biotechnology in gene therapy, immunotherapy, drug delivery systems, and artificial intelligence in medicine."
—From the Foreword by C. L. Khetrapal, Distinguished Professor & Founder Director of Centre of Biomedical Research, Sanjay Gandhi Post Institute of Medical Sciences Campus, Lucknow, Uttar Pradesh, India