Responding to the growth of research in the field over the past decade, this book brings together leading investigators with expertise in pulmonology, pathology, and developmental biology to clarify the mechanisms that regulate the development of bronchial vascular remodeling in asthma and COPD, as well as explore the pathophysiological processes that may impact the formulation of new therapeutic strategies for these conditions.
Table of Contents
Developmental Origins of the Bronchial Vasculature: Experimental Approaches to Study the Structure and Function of Bronchial Vasculature. Noninvasive Measurement of Airway Blood Flow. Molecular Mechanisms of Angiogenesis. Chemokine Regulation of Angiogenesis. The Role of the Extracellular Matrix in Angiogenesis. Angiogenesis in the Asthmatic Airway. Bronchial Vascular Remodeling in Emphysema/Chronic Bronchitis. Pulmonary Vascular Remodeling in COPD. Angiogenesis: Lessons Learned From Skeletal Muscle. Pharmacologic Modulation of Bronchial Vascular Remodeling: Current Therapies and Novel Approaches
“…The quality of this book is excellent. Color illustrations and better tables and diagrams would have complemented the high quality clinical material. This book will be extremely useful for clinicians evaluating and managing patients with pulmonary hypertension. In bringing transatlantic expertise together to give us comprehensive basic science clinical research as well as therapeutic implications of airway remodeling, the author has done a commendable job.”
—Doody’s Review Services
diagrams are excellent and allow the reader to appreciate immediately the extensive nature of the bronchial supply…I would recommend this book to pulmonary specialists, particularly those active in research.
–Respiratory Care Review