1st Edition

CNS Neurotransmitters and Neuromodulators
Glutamate



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ISBN 9780849376313
Published July 25, 1995 by CRC Press
400 Pages

USD $450.00

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Book Description

CNS Neurotransmitters and Neuromodulators is an indispensable and comprehensive reference for any research worker involved with glutamate in the CNS. An impressive group of well-known authors contribute up-to-date reviews that offer a global picture of the state of research in the area.
The authors cover a wide range of interdisciplinary aspects of the subject, including anatomical, physiological, and biochemical. Topics in this volume range from the localization of synthetic enzymes through electrophysiology, pharmacology, and molecular biology to behavioral importance in learning and memory. No other single volume offers the depth or broad scope of material found here.
In addition to being a definitive reference work, CNS Neurotransmitters and Neuromodulators is the perfect one-step introduction to glutamate in the CNS for undergraduates, postgraduates, or established researchers who want a comprehensive overview text to keep abreast of developments in several areas of neuroscience.

Table of Contents

Localisation of Glutamate and Its Membrane Transport Proteins, J. Storm-Mathisen, N.C. Danbolt, and O.P. Ottersen
Glutamate Synthesis, Metabolism, and Uptake, F. Fonnum and B. Hassel
The Release of Glutamate from Synaptic Terminals, D.G. Nicholls
Molecular Structure of Glutamate Receptor Channels, C.D. Blackstone and R.L. Huganir
Characterisation and Modulation of Binding to Glutamate Receptors, P.J. Roberts and R.H.P. Porter
The Distribution of Glutamate Receptor Subtypes in Mammalian CNS using Quantitative in vitro Autoradiography, L.S. Dure I V and A.B. Young
Subtypes of Glutamate Receptors: Pharmacological Classification, E.W. Harris
Glutamate-Activated Ion Channels, V. Vodyanoy
Metabotropic Glutamate Receptors, R. Anwyl
Nitric Oxide and Glutamate Receptors, P.P. McCaslin and S. Oh
Biochemical Transduction Systems Operated by Excitatory Amino Acids, P.J. Conn, D.S. Chung, D.G. Winder, R.W. Gereau IV, and V. Boss
The Role of Glutamate and Its Receptors in Synaptic Transmission, T.P. Hicks
Excitatory Amino Acids and Seizures, M.A. Rogawski
Glutamate Receptors and Neurotoxicity, A. Schousboe and A. Frandsen
Glutamate in Neurodegenerative Disorders, C. Ikonomidou and L. Turski
Excitatory Amino Acids and Growth Factors: Biological and Molecular Interactions Regulating Neuronal Survival and Plasticity, S.W. Barger and M.P. Mattson
Glutamate Receptors and Immediate Early Gene Expression, B.J. Morris
Modulation of Glutamate Receptor Function by Polyamines, I.J. Reynolds
Role of NMDA Receptors in Behavior and Behavioral Effects of Drugs, J.M. Witkin
Behavioral Effects of Non-NMDA Glutamate Receptor Antagonists, R. Lalonde
Glutamate and the Hypothalamo-Pituitary-Gonadal Axis, A-M. Cowell

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Reviews

"...this book admirably achieves its goal of providing a convenient one-stop overview of EAA neurotransmission...highly recommended for the library of any department engaged in neurobiological research."
-John W. Farkany, J. Med. Chem., 1996, 39(3)