Optically active compounds are gaining ever-increasing importance in organic chemistry, both in the academic and the industrial arenas. The rational synthesis of the growing number of chiral chemicals, drugs, and natural products demands efficient methods for producing these compounds in an enantiomerically, highly pure form. Despite the available
Introduction. Basic Concepts and Nomenclature of Stereochemistry. Resolution by Formation and Fractional Crystallisation of Diastereomeric Salts. Resolving Agents. Selection of the Resolving Agent. Resolution in Practice, Selection of the Optimal Parameters. Alternative Methods of Resolution by Diastereomeric Salt Formation. Detailed Descriptions of Selected Resolutions. Appendices.