As a distinct class of macromolecules, viruses are continually being studied in order to determine their properties. Following a knowledge of host-range infectivity, the particle mass-molecular weight of the virus and related properties - including size, shape, sedimentation, and diffusion coefficients - are also important characterizations.
In the literature, these values have been determined for many viruses, and a variety of techniques are available by which such properties may be analyzed. Until now, there has been no single source for such information that the interested investigator may consult, and no databases provided this kind of information.
CRC Handbook of Viruses: Mass-Molecular Weight Values and Related Properties corrects this deficiency by presenting such data for all classes of viruses; centering on viruses, their molecular weight, and their related properties; and acquainting the investigator to many methods for obtaining the mass-molecular weight value of viruses. This singular study explains the variety of methods available to the researcher as well as provides examples of each method. Molecular weight values are accessed directly from the book, saving the investigator a tedious search through the range of literature.
CRC Handbook of Viruses serves the:
Viruses As Macromolecules
The Macromolecule Concept
Nucleic Acid Structure
Viruses As Nucleoproteins
Physical Properties in the Construction of Regular Viruses
Crystallography - Basic Aspects
Molecular Weight Determinations from Sedimentation Experiments
Density Gradient Centrifugation
Supplementary Procedures for Obtaining M from Values of Density, the Partial Specific Volume, Viscosity, and the Frictional Coefficient
Mass-Molecular Weight Determinations from Scattering Studies
Small Angle X-Ray Scattering
Small Angle Neutron Scattering
Classical Light Scattering
Hydrodynamic Sizing and Solvation
Laser Light Scattering
High Flux X-Ray and Neutron Scattering
Resistive Pulse Technique
Hydrodynamic Radii and Solvation