Cardiac Remodeling: Mechanisms and Treatment, 1st Edition (Hardback) book cover

Cardiac Remodeling

Mechanisms and Treatment, 1st Edition

Edited by Barry Greenberg

CRC Press

600 pages | 22 Color Illus. | 141 B/W Illus.

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Hardback: 9780824723873
pub: 2005-09-29
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Description

Exploring the causes, mechanisms, and pathophysiology of cardiac remodeling, this reference offers detailed descriptions of the various components of the remodeling process, as well as new therapeutic interventions and recent and future prospects for the treatment of cardiac remodeling.

Table of Contents

Overview: What is Cardiac Remodeling? Structural and Mechanical Aspects of Remodeling. What Differentiates Physiological from Pathophysiologic Remodeling? Myocyte Signaling During the Transition from Hypertrophy to Heart Failure. Cardiac Myocyte Structural Remodeling. Myocyte Loss and Regeneration During Cardiac Remodeling. Role of the Interstitial Matrix in Maintaining Cardiac Function. Changes in the Interstitial Matrix During Cardiac Remodeling. Bioenergetic Abnormalities in the Remodeling Heart. Experimental Animal Models of Remodeling. The Use of Transgenic Animals to Study Cardiac Remodeling. The Effects of Pressure and Volume Load on Cardiac Structure and Remodeling. The Role of the Renin-Angiotensin Aldosterone System in Cardiac Remodeling. Adrenergic Pathways that Result in Cardiac Remodeling. Cytokines and Their Effects on Cardiac Remodeling. Other Factors Related to Cardiac Remodeling. Functional Consequences of the Remodeling Process. Epidemiology of Cardiac Remodeling. Clinical Assessment of Remodeling. Inhibition of the Renin-Angiotensin Aldosterone System. Effects of Adrenergic Blockade on Remodeling. Other Medical Therapies for Treating Cardiac Remodeling. The Effects of Cardiac Revascularization on the Remodeling Process. Valve Replacement and Repair. Cardiac Remodeling After LVAD Replacement. Cardiac Resynchronization Therapy. Other Surgical or Device-Based Approaches to Treating Cardiac Remodeling. Gene Transfer Therapy in the Treatment of Cardiac Remodeling. Future Strategies for Reversing the Remodeling Process

About the Authors/Editor

Greenberg\, Barry

About the Series

Fundamental and Clinical Cardiology

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Subject Categories

    BISAC Subject Codes/Headings:
    MED000000
    MEDICAL / General
    MED010000
    MEDICAL / Cardiology