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Carnitine Metabolism and Human Nutrition




ISBN 9781466554269
Published June 26, 2014 by CRC Press
186 Pages - 11 B/W Illustrations

 
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Book Description

Carnitine Metabolism and Human Nutrition offers a contemporary and in-depth look at the biological effects of carnitine metabolism and its application to clinical and sports nutrition, based on decades of robust scientific enquiry. It gathers and distills key results of the last 20 years of carnitine research to provide an invaluable reference tool for students, researchers, and clinicians.

This book addresses the importance of carnitine in skeletal muscle fuel metabolism, the complexities and importance of muscle carnitine transport, and the metabolic insight that has been gained from experiments manipulating muscle carnitine stores. The authors cover the potential application of carnitine supplementation in specific clinical populations and the role of carnitine as an ergogenic aid for athletes. They also provide a comprehensive mechanistic overview of skeletal muscle insulin resistance, including the role of carnitine shuttle systems in the metabolic abnormalities associated with obesity and the metabolic syndrome.

Carnitine Metabolism and Human Nutrition provides you with a comprehensive and up-to-date look at the properties and underlying metabolic biochemistry of carnitine. The book provides contributions from leading international scientists, each a pioneer in their chosen study of carnitine metabolism or its application to human nutrition.

Table of Contents

Section I: Carnitine homeostasis and tissue metabolism

Carnitine homeostasis in humans
Peggy Borum

Carnitine and energy metabolism
Tariq R. Altamimi and Gary D. Lopaschuk

Section II: Carnitine transport and metabolism in skeletal muscle

The role of carnitine in the integration of skeletal muscle fuel metabolism
Craig Porter

Skeletal muscle carnitine transport
Francis B. Stephens

The metabolic impact of manipulating the muscle carnitine pool
Benjamin T. Wall

Section III: Applications of carnitine in human nutrition

Carnitine metabolism and nutrition in dialysis patients
Eric P. Brass

Carnitine metabolism and nutrition in insulin resistance and type 2 diabetes
Shawna Wicks, Robert Noland, and Randall Mynatt

Carnitine metabolism and nutrition in peripheral vascular disease
Giusseppe Maria Andreozzi

Carnitine as an ergogenic aid for sports performance
Stuart D.R. Galloway and Elizabeth M. Broad

Conclusions and future directions
Craig Porter and Benjamin T. Wall

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