Within the last 10 years, the immune system of ruminants, especially T cells and their interactions with other cells, has been an important topic of study for veterinary immunologists and an area of interest for medical and fundamental immunologists. This book brings together all the latest data on ruminant cell-mediated immunology. In the first half of the book, leukocytes and their membrane molecules and cytokines are reviewed. Markers, tissue distribution, functional characterization, ontogeny, cytokines, and histocompatibility are covered in depth in separate chapters. In the second half of the book, cell-mediated immune responses against infectious diseases such as East Coast fever, infectious bovine rhinotracheitis, foot and mouth disease, maedi-visna, and gastrointestinal nematodes are analyzed. The application of cytokines to ruminants against infectious diseases is also reviewed.
Table of Contents
The Leukocytes: Markers, Tissue Distribution, and Functional Characterization, C.J. Howard and W.I. Morrison.
Ontogeny of T Cells, W.R. Hein.
The Major Histocompatibility Complex, L. Andersson and C.J. Davies.
The T Cell Receptor, N. Ishiguro and W.R. Hein.
The Cytokines: Origin, Structure, and Function, D.M. Haig, C.J. McInnes, P.R. Wood, and H.F. Seow.
Induction of T Cell-Mediated Immune Responses in Ruminants, D.J. McKeever.
Lymphocyte Recirculation and Homing, W.G. Kimpton, E.A. Washington, and R.N. Cahill.
Neutrophils and Killer Cells, J.A. Roth.
East Coast Fever (Theileria parva): Cell-Mediated Immunity and Protection, B.M.L. Goddeeris, W.I. Morrison, E.L. Taracha, and D.J. McKeever.
Infectious Bovine Rhinotracheitis (Bovine Herpesvirus 1): Helper T Cells, Cytotoxic T Cells, and NK Cells, M. Denis, G. Splitter, E. Thiry, P.-P. Pastoret, and L.A. Babiuk.
Foot and Mouth Disease (Aphthovirus): Viral T Cell Epitopes, T. Collen.
Maedi-Visni (Lentivirus): Cell-Mediated Immune Responses in Pathogenesis, B.A. Blacklaws, P. Bird, and I. McConnell.
Cell-Mediated Responses against Gastrointestinal Nematode Parasites of Ruminants, S.J. McClure and D.L. Emery.
Cytokine Application in Infectious Diseases, M. Campos, D.L. Godson, H.P.A. Hughes, and L.A. Babiuk.