### Algorithms for Next-Generation Sequencing

Due to advances in sequencing technology, we can view hundreds of millions of short reads in a few days. Sequencing technology enables us to study our genome on a large scale, but it also introduces new challenges, such as how to process vast amounts of data efficiently and how to summarize so much…

Hardback – 2017-04-01

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### An Introduction to Physical Oncology

#### How Mechanistic Mathematical Modeling Can Improve Cancer Therapy Outcomes

This book presents a theoretical multiscale modeling framework for the integration of processes spanning from molecular signaling to individual and collective cellular behavior to complex spatiotemporal dynamics at the tissue and organ levels. It then gives a detailed discussion on how to…

Hardback – 2017-03-31

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Statistical Modeling and Machine Learning for Molecular Biology

The goal of this introductory graduate textbook is to cover the statistical and computational methods needed by molecular biologists in order to analyze their own data without the help of a bioinformatics expert. The book covers several of the major data analysis techniques used to analyze data…

Paperback – 2016-12-12

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Introduction to Mathematical Oncology

Introduction to Mathematical Oncology presents biologically well-motivated and mathematically tractable models that facilitate both a deep understanding of cancer biology and better cancer treatment designs. It covers the medical and biological background of the diseases, modeling issues, and…

Hardback – 2016-02-18

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Big Data Analysis for Bioinformatics and Biomedical Discoveries

Demystifies Biomedical and Biological Big Data Analyses Big Data Analysis for Bioinformatics and Biomedical Discoveries provides a practical guide to the nuts and bolts of Big Data, enabling you to quickly and effectively harness the power of Big Data to make groundbreaking biological discoveries,…

Hardback – 2015-12-22

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### RNA-seq Data Analysis

#### A Practical Approach

The State of the Art in Transcriptome AnalysisRNA sequencing (RNA-seq) data offers unprecedented information about the transcriptome, but harnessing this information with bioinformatics tools is typically a bottleneck. RNA-seq Data Analysis: A Practical Approach enables researchers to examine…

Pack - Book & Ebook – 2014-09-19

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Computational and Visualization Techniques for Structural Bioinformatics Using Chimera

A Step-by-Step Guide to Describing Biomolecular Structure Computational and Visualization Techniques for Structural Bioinformatics Using Chimera shows how to perform computations with Python scripts in the Chimera environment. It focuses on the three core areas needed to study structural…

Pack - Book & Ebook – 2014-07-29

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Bayesian Phylogenetics

#### Methods, Algorithms, and Applications

Offering a rich diversity of models, Bayesian phylogenetics allows evolutionary biologists, systematists, ecologists, and epidemiologists to obtain answers to very detailed phylogenetic questions. Suitable for graduate-level researchers in statistics and biology, Bayesian Phylogenetics: Methods,…

Hardback – 2014-05-27

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Managing Your Biological Data with Python

Take Control of Your Data and Use Python with Confidence Requiring no prior programming experience, Managing Your Biological Data with Python empowers biologists and other life scientists to work with biological data on their own using the Python language. The book teaches them not only how to…

Paperback – 2014-03-18

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Stochastic Dynamics for Systems Biology

Stochastic Dynamics for Systems Biology is one of the first books to provide a systematic study of the many stochastic models used in systems biology. The book shows how the mathematical models are used as technical tools for simulating biological processes and how the models lead to conceptual…

Hardback – 2014-03-11

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Systems Biology

#### Mathematical Modeling and Model Analysis

Drawing on the latest research in the field, Systems Biology: Mathematical Modeling and Model Analysis presents many methods for modeling and analyzing biological systems, in particular cellular systems. It shows how to use predictive mathematical models to acquire and analyze knowledge about…

Hardback – 2013-11-12

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Statistical Methods for QTL Mapping

While numerous advanced statistical approaches have recently been developed for quantitative trait loci (QTL) mapping, the methods are scattered throughout the literature. Statistical Methods for QTL Mapping brings together many recent statistical techniques that address the data complexity of QTL…

Hardback – 2013-11-01

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Introduction to Biological Networks

The new research area of genomics-inspired network biology lacks an introductory book that enables both physical/computational scientists and biologists to obtain a general yet sufficiently rigorous perspective of current thinking. Filling this gap, Introduction to Biological Networks provides a…

Hardback – 2013-04-24

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Game-Theoretical Models in Biology

Covering the major topics of evolutionary game theory, Game-Theoretical Models in Biology presents both abstract and practical mathematical models of real biological situations. It discusses the static aspects of game theory in a mathematically rigorous way that is appealing to mathematicians. In…

Hardback – 2013-03-27

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Cellular Potts Models

#### Multiscale Extensions and Biological Applications

A flexible, cell-level, and lattice-based technique, the cellular Potts model accurately describes the phenomenological mechanisms involved in many biological processes. Cellular Potts Models: Multiscale Extensions and Biological Applications gives an interdisciplinary, accessible treatment of…

Hardback – 2013-03-26

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Genome Annotation

The success of individualized medicine, advanced crops, and new and sustainable energy sources requires thoroughly annotated genomic information and the integration of this information into a coherent model. A thorough overview of this field, Genome Annotation explores automated genome analysis and…

Hardback – 2012-08-30

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Quantitative Biology

#### From Molecular to Cellular Systems

Quantitative methods are revolutionizing modern molecular and cellular biology. Groundbreaking technical advances are fueling the rapid expansion in our ability to observe, as seen in multidisciplinary studies that integrate theory, computation, experimental assays, and the control of…

Hardback – 2012-08-25

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Computational Systems Biology of Cancer

The future of cancer research and the development of new therapeutic strategies rely on our ability to convert biological and clinical questions into mathematical models—integrating our knowledge of tumour progression mechanisms with the tsunami of information brought by high-throughput…

Hardback – 2012-08-25

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition

Richly illustrated in color, Statistics and Data Analysis for Microarrays Using R and Bioconductor, Second Edition provides a clear and rigorous description of powerful analysis techniques and algorithms for mining and interpreting biological information. Omitting tedious details, heavy formalisms,…

Hardback – 2011-12-06

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Stochastic Modelling for Systems Biology, Second Edition

Since the first edition of Stochastic Modelling for Systems Biology, there have been many interesting developments in the use of "likelihood-free" methods of Bayesian inference for complex stochastic models. Re-written to reflect this modern perspective, this second edition covers everything…

Hardback – 2011-11-09

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Dynamics of Biological Systems

From the spontaneous rapid firing of cortical neurons to the spatial diffusion of disease epidemics, biological systems exhibit rich dynamic behaviour over a vast range of time and space scales. Unifying many of these diverse phenomena, Dynamics of Biological Systems provides the computational and…

Hardback – 2011-08-25

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Introduction to Bio-Ontologies

Introduction to Bio-Ontologies explores the computational background of ontologies. Emphasizing computational and algorithmic issues surrounding bio-ontologies, this self-contained text helps readers understand ontological algorithms and their applications. The first part of the book defines…

Hardback – 2011-06-22

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Biological Computation

The area of biologically inspired computing, or biological computation, involves the development of new, biologically based techniques for solving difficult computational problems. A unified overview of computer science ideas inspired by biology, Biological Computation presents the most fundamental…

Hardback – 2011-05-25

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Introduction to Proteins

#### Structure, Function, and Motion

As the tools and techniques of structural biophysics assume greater roles in biological research and a range of application areas, learning how proteins behave becomes crucial to understanding their connection to the most basic and important aspects of life. With more than 350 color images…

Hardback – 2010-12-17

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Introduction to Computational Proteomics

Introduction to Computational Proteomics introduces the field of computational biology through a focused approach that tackles the different steps and problems involved with protein analysis, classification, and meta-organization. The book starts with the analysis of individual entities and works…

Hardback – 2010-12-09

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Multiscale Cancer Modeling

Cancer is a complex disease process that spans multiple scales in space and time. Driven by cutting-edge mathematical and computational techniques, in silico biology provides powerful tools to investigate the mechanistic relationships of genes, cells, and tissues. It enables the creation of…

Hardback – 2010-12-08

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Clustering in Bioinformatics and Drug Discovery

With a DVD of color figures, Clustering in Bioinformatics and Drug Discovery provides an expert guide on extracting the most pertinent information from pharmaceutical and biomedical data. It offers a concise overview of common and recent clustering methods used in bioinformatics and drug discovery.…

Hardback – 2010-11-15

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Methods in Medical Informatics

#### Fundamentals of Healthcare Programming in Perl, Python, and Ruby

Too often, healthcare workers are led to believe that medical informatics is a complex field that can only be mastered by teams of professional programmers. This is simply not the case. With just a few dozen simple algorithms, easily implemented with open source programming languages, you can fully…

Hardback – 2010-09-22

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Computational Hydrodynamics of Capsules and Biological Cells

Spanning biological, mathematical, computational, and engineering sciences, computational biofluiddynamics addresses a diverse family of problems involving fluid flow inside and around living organisms, organs, tissue, biological cells, and other biological materials. Computational Hydrodynamics of…

Hardback – 2010-06-02

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Cancer Systems Biology

The unprecedented amount of data produced with high-throughput experimentation forces biologists to employ mathematical representation and computation methods to glean meaningful information in systems-level biology. Applying this approach to the underlying molecular mechanisms of tumorigenesis,…

Hardback – 2010-05-04

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Handbook of Chemoinformatics Algorithms

Unlike in the related area of bioinformatics, few books currently exist that document the techniques, tools, and algorithms of chemoinformatics. Bringing together worldwide experts in the field, the Handbook of Chemoinformatics Algorithms provides an overview of the most common chemoinformatics…

Hardback – 2010-04-21

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Cell Mechanics

#### From Single Scale-Based Models to Multiscale Modeling

Ubiquitous and fundamental in cell mechanics, multiscale problems can arise in the growth of tumors, embryogenesis, tissue engineering, and more. Cell Mechanics: From Single Scale-Based Models to Multiscale Modeling brings together new insight and research on mechanical, mathematical, physical, and…

Hardback – 2010-01-27

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Algorithms in Bioinformatics

#### A Practical Introduction

Thoroughly Describes Biological Applications, Computational Problems, and Various Algorithmic Solutions Developed from the author’s own teaching material, Algorithms in Bioinformatics: A Practical Introduction provides an in-depth introduction to the algorithmic techniques applied in…

Hardback – 2009-11-24

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Glycome Informatics

#### Methods and Applications

A Focused, State-of-the-Art Overview of This Evolving FieldPresents Various Techniques for Glycoinformatics The development and use of informatics tools and databases for glycobiology and glycomics research have increased considerably in recent years. In addition to accumulating well-structured…

Hardback – 2009-11-19

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Biological Sequence Analysis Using the SeqAn C++ Library

An Easy-to-Use Research Tool for Algorithm Testing and Development Before the SeqAn project, there was clearly a lack of available implementations in sequence analysis, even for standard tasks. Implementations of needed algorithmic components were either unavailable or hard to access in third-party…

Hardback – 2009-11-11

CRC Press*Chapman & Hall/CRC Mathematical and Computational Biology*### Differential Equations and Mathematical Biology, Second Edition

Deepen students’ understanding of biological phenomena Suitable for courses on differential equations with applications to mathematical biology or as an introduction to mathematical biology, Differential Equations and Mathematical Biology, Second Edition introduces students in the physical,…

Hardback – 2009-11-09

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Python for Bioinformatics

Programming knowledge is often necessary for finding a solution to a biological problem. Based on the author’s experience working for an agricultural biotechnology company, Python for Bioinformatics helps scientists solve their biological problems by helping them understand the basics of…

Paperback – 2009-09-30

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Spatial Ecology

Exploring the relationship between mathematics and ecology, Spatial Ecology focuses on some important emerging challenges in the field. These challenges consist of understanding the impact of space on community structure, incorporating the scale and structure of landscapes into mathematical models,…

Hardback – 2009-08-05

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Gene Expression Studies Using Affymetrix Microarrays

The Affymetrix GeneChip® system is one of the most widely adapted microarray platforms. However, due to the overwhelming amount of information available, many Affymetrix users tend to stick to the default analysis settings and may end up drawing sub-optimal conclusions. Written by a molecular…

Hardback – 2009-07-15

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Engineering Genetic Circuits

An Introduction to Systems BioengineeringTakes a Clear and Systematic Engineering Approach to Systems Biology Focusing on genetic regulatory networks, Engineering Genetic Circuits presents the modeling, analysis, and design methods for systems biology. It discusses how to examine experimental data…

Hardback – 2009-07-14

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Meta-analysis and Combining Information in Genetics and Genomics

Novel Techniques for Analyzing and Combining Data from Modern Biological StudiesBroadens the Traditional Definition of Meta-Analysis With the diversity of data and meta-data now available, there is increased interest in analyzing multiple studies beyond statistical approaches of formal…

Hardback – 2009-07-07

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R

Emphasizing the search for patterns within and between biological sequences, trees, and graphs, Combinatorial Pattern Matching Algorithms in Computational Biology Using Perl and R shows how combinatorial pattern matching algorithms can solve computational biology problems that arise in the analysis…

Hardback – 2009-04-08

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Structural Bioinformatics

#### An Algorithmic Approach

The Beauty of Protein Structures and the Mathematics behind Structural BioinformaticsProviding the framework for a one-semester undergraduate course, Structural Bioinformatics: An Algorithmic Approach shows how to apply key algorithms to solve problems related to macromolecular structure. Helps…

Hardback – 2008-10-30

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Kinetic Modelling in Systems Biology

With more and more interest in how components of biological systems interact, it is important to understand the various aspects of systems biology. Kinetic Modelling in Systems Biology focuses on one of the main pillars in the future development of systems biology. It explores both the methods and…

Hardback – 2008-10-24

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Handbook of Hidden Markov Models in Bioinformatics

Demonstrating that many useful resources, such as databases, can benefit most bioinformatics projects, the Handbook of Hidden Markov Models in Bioinformatics focuses on how to choose and use various methods and programs available for hidden Markov models (HMMs). The book begins with discussions…

Hardback – 2008-06-12

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Spatiotemporal Patterns in Ecology and Epidemiology

#### Theory, Models, and Simulation

Although the spatial dimension of ecosystem dynamics is now widely recognized, the specific mechanisms behind species patterning in space are still poorly understood and the corresponding theoretical framework is underdeveloped. Going beyond the classical Turing scenario of pattern formation,…

Hardback – 2007-12-26

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Bioinformatics

#### A Practical Approach

An emerging, ever-evolving branch of science, bioinformatics has paved the way for the explosive growth in the distribution of biological information to a variety of biological databases, including the National Center for Biotechnology Information. For growth to continue in this field, biologists…

Hardback – 2007-08-20

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Pattern Discovery in Bioinformatics

#### Theory & Algorithms

The computational methods of bioinformatics are being used more and more to process the large volume of current biological data. Promoting an understanding of the underlying biology that produces this data, Pattern Discovery in Bioinformatics: Theory and Algorithms provides the tools to study…

Hardback – 2007-07-04

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Optimal Control Applied to Biological Models

From economics and business to the biological sciences to physics and engineering, professionals successfully use the powerful mathematical tool of optimal control to make management and strategy decisions. Optimal Control Applied to Biological Models thoroughly develops the mathematical aspects of…

Hardback – 2007-05-07

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*### Niche Modeling

#### Predictions from Statistical Distributions

Using theory, applications, and examples of inferences, Niche Modeling: Predictions from Statistical Distributions demonstrates how to conduct and evaluate niche modeling projects in any area of application. It features a series of theoretical and practical exercises for developing and evaluating…

Hardback – 2006-12-15

Chapman and Hall/CRC*Chapman & Hall/CRC Mathematical and Computational Biology*

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