The contents of this book are focused on the use of chemical modification to study the properties of proteins in solution. Particular emphasis has been placed on the practical laboratory aspects of this approach to the study of the relationship between structure and function in the complex class of biological heteropolymers.
1. The Chemical Modification of Proteins 2. Amino Acid Analysis 3. Peptide Separation by Reverse-Phase High Performance Liquid 4. Methods for Sequence Determination 5. Chemical Cleavage of Peptide Bonds 6. The Modification of Cysteine 7. The Modification of Cystine - Cleavage of Disulfide Bonds 8. The Modification of Methionine 9. Modification of Histidine Residues 10. The Modification of Lysine