Chemical Warfare Agents: Chemistry, Pharmacology, Toxicology, and Therapeutics, Second Edition, 2nd Edition (Hardback) book cover

Chemical Warfare Agents

Chemistry, Pharmacology, Toxicology, and Therapeutics, Second Edition, 2nd Edition

Edited by Brian J. Lukey, James A. Romano Jr., James A. Romano, Harry Salem, Brian J Lukey, Harry Salem

CRC Press

752 pages | 130 B/W Illus.

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Hardback: 9781420046618
pub: 2007-12-17
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Description

The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11th, 2001. Reflecting a greater sense of urgency within the field of chemical defense since this event, research related to chemical warfare agents (CWAs) continues to expand at a remarkable pace.

Chemical Warfare Agents: Pharmacology, Toxicology, and Therapeutics, Second Edition explores the latest methods and products for preventing, diagnosing, and treating the acute and chronic effects of toxic CWA exposure. This edition citesthe key developments in chemical defense research since 2001, including new epidemiological or clinical studies of exposed or potentially exposed populations; new treatment concepts and products; improved organization of the national response apparatus in the U.S. addressing the potential for CWA terrorism; and improved diagnostic tests that enable rapid diagnosis and treatment.

Leading researchers explain how these breakthroughs help researchers determine physiologically relevant detection thresholds and develop more effective countermeasures and national response procedures. Chemical Warfare Agents provides first responders and emergency medical teams with the most up-to-date information they need to prepare for and handle natural disasters, chemical spills, terrorism, and warfare situations—quickly and effectively.

Reviews

Reviews of the First Edition:

“…There is something here for everyone with an interest in chemical warfare agents. I recommend it for those interested in research or for those who are formulating plans for response to terrorism.”

Wilderness & Environmental Medicine

“This book is a must-read for any scientist interested in the role of the neurotransmitter acetylcholine. The detailed references along with nonjudgmental descriptions as to any causal relationship for the development of chronic neuropsychiatric disease make this a valuable informational source…“

— Doody’s Publishing

the First Edition:

“…There is something here for everyone with an interest in chemical warfare agents. I recommend it for those interested in research or for those who are formulating plans for response to terrorism.”

Wilderness & Environmental Medicine

“This book is a must-read for any scientist interested in the role of the neurotransmitter acetylcholine. The detailed references along with nonjudgmental descriptions as to any causal relationship for the development of chronic neuropsychiatric disease make this a valuable informational source…“

— Doody’s Publishing

Table of Contents

Brief History and Use of Chemical Warfare Agents in Warfare and Terrorism; H. Salem, A.L. Ternay Jr., and J.K. Smart

The Chemistry of Chemical Warfare Agents; P. Kikilo, V. Fedorenko, and A.L. Ternay Jr.

Chemical Warfare Agent Threat to Drinking Water; H. Salem, C.E. Whalley, C.H. Wick, T.P. Gargan II, and W.D. Burrows

Health Effects of Low-Level Exposure to Nerve Agents; J.H. McDonough and J.A. Romano Jr.

Toxicokinetics of Nerve Agents; M.J. van der Schans, H.P. Benschop, and C.E. Whalley

Application of Genomic, Proteomic, and Metabolomic Technologies to the Development of Countermeasures Against Chemical Warfare Agents; J.W. Sekowski and J.F. Dillman

Novel Approaches to Medical Protection Against Chemical Warfare Nerve Agents; A. Saxena, C. Luo, N. Chilukuri, D.M. Maxwell, and B.P. Doctor

Nerve Agent Bioscavengers: Progress in Development of a New Mode of Protection Against Organophosphorus Exposure; D.E. Lenz, C.A. Broomfield, D.T. Yeung, P. Masson, D.M. Maxwell, and D.M. Cerasoli

Butyrylcholinesterase and Its Synthetic C-terminal Peptide Confer In Vitro Suppression of Amyloid Fibrils Formation; E. Podoly, S. Diamant, A. Friedler, O. Livnah, and H. Soreq

A Novel Medical Countermeasure for Organophosphorus Intoxication: Connection to Alzheimer’s Disease and Dementia; Edna F.R. Pereira, D.R. Burt, Y. Aracava, R.K. Kan, T.A. Hamilton, J.A. Romano Jr., M. Adler, and E.X. Albuquerque

Inhalation Toxicology of Nerve Agents; P.A. Dabisch, S.W. Hulet, R. Kristovich, and R.J. Mioduszewski

Vesicants and Oxidative Stress; M.G. Smith, W. Stone, R.F. Guo, P.A. Ward, S. Mukherjee, S.K. Das, and Z. Suntres

Health Effects of Exposure to Vesicant Agents; C.G. Hurst and W.J. Smith

Cyanides: Toxicology, Clinical Presentation, and Medical Management; B. Ballantyne and H. Salem

Chemicals Used for Riot Control and Personal Protection; H. Salem, B. Ballantyne, and S. Katz

Mechanism of Action of Botulinum Neurotoxin and Overview of Medical Countermeasure Development for Intoxication; M. Adler, G. Oyler, J.P. Apland, S.S. Deshpande, J.D. Nicholson, J. Anderson, C. Millard, and F.J. Lebeda

Ricin and Related Toxins: Review and Perspective; C.B. Millard and R.D. LeClaire

Screening Smokes: Applications, Toxicology, Clinical Considerations, and Medical Management; B. Ballantyne and H. Salem

Clinical Detection of Exposure to Chemical Warfare Agents; B.R. Capacio, J.R. Smith, R.K. Gordon, J.R. Haigh, J. Barr, and B.J. Lukey

Personal Protective Equipment (PPE): Practical and Theoretical Considerations; M.R. Jones

Chemical Warfare Agent Decontamination from Skin; B.J. Lukey, H.F. Slife Jr., E. Clarkson, C.G. Hurst, and E.H. Braue Jr.

Chemical Warfare, Chemical Terrorism, and Traumatic Stress Responses: An Assessment of Psychological Impact; J.A. Romano Jr., L. Lumley, J.M. King, and G.A. Saviolakis

Emergency Response to a Chemical Warfare Agent Incident: Domestic Preparedness, First Response, and Public Health Considerations; D.H. Moore and B. Saunders-Price

Emergency Medical Response to a Chemical Terrorist Attack; S.A. Pulley and M.R. Jones Index

Subject Categories

BISAC Subject Codes/Headings:
MED096000
MEDICAL / Toxicology
POL037000
POLITICAL SCIENCE / Political Freedom & Security / Terrorism
SOC040000
SOCIAL SCIENCE / Disasters & Disaster Relief