1st Edition

Chemistry and Biology of Beta Lactams

By Bimal Krishna Banik, Aparna Das Copyright 2025
    424 Pages 411 B/W Illustrations
    by CRC Press

    Due to their medicinal activity and potential use as synthetic starting materials, studies on beta-lactams have increased significantly. This unique volume takes readers on a tour de force from the concept of antibiosis, to the serendipity of antibiotics, evolution of beta‐lactam development, and the molecular biology of antibiotic resistance. These areas of research have culminated in a deeper understanding of microbiology, particularly in the area of bacterial cell wall synthesis and recycling. Considerable work has been performed by chemists and biologists to continue updating their findings about beta-lactam synthesis.


    • Stereoselective Synthesis of Monocyclic, Bicyclic and Polycyclic Beta-Lactams
    • Microwave, Ultrasound and Solid Support-Mediated Preparation of Beta Lactams
    • Diverse Medicinal Activities Including Anticancer Activities of Beta Lactams and Products Obtained from Them
    • Nanoparticles, Artificial Intelligence and Dipole Moments in Beta Lactam Science
    • Synthesis and Mechanism of Formation of Polyaromatic Beta Lactams 


    1. Beta Lactams: Classifications, Biogenesis, Physical Characteristics and Medicinal Activities
    2. Monocyclic Beta-Lactams: Stereocontrolled Synthesis by Diverse Methods
    3. Polycyclic Beta Lactams: Synthesis by Diverse Methods
    4. Polyaromatic Beta Lactams: Synthesis and Anticancer Activities
    5. Microwave and Ultrasound in Beta-Lactam Chemistry
    6. Solid Support-Mediated Beta Lactam Synthesis
    7. Mechanism of Beta-Lactam Synthesis by Cycloaddition Reaction
    8. Beta Lactams as Synthons for Diverse Heterocycles
    9. Medicinal Activities of Beta Lactams as Antibacterials and Their Mechanism of Action
    10. Antibacterial effects of beta-lactam antibiotics with nanoparticles
    11. The Effects of Dipole Moments on the Biological Activities of Diverse Beta Lactams
    12.  Artificial Intelligence on Beta Lactams Research


    Dr. Bimal Krishna Banik has a remarkable career, spanning significant achievements in teaching, research, mentoring, and professional service.  He completed his Ph. D. degree in Chemistry from the Indian Association for the Cultivation of Science, Calcutta. Then, he pursued postdoctoral research at Case Western Reserve University, Ohio and Stevens Institute of Technology, New Jersey.  Dr. Banik was a Tenured Full Professor in Chemistry and First President’s Endowed Professor in Science & Engineering at the University of Texas-Pan American. He was the Vice President of Research & Education Development at the Community Health Systems of Texas.  Currently, Dr. Banik is a Full Professor at the Prince Mohammad Bin Fahd University, Kingdom of Saudi Arabia. Notably, he has been selected as a Fellow of Five International Scientific Societies and has been designated as a Distinguished Researcher/Distinguished Scientist. 

    Dr. Aparna Das obtained her Ph. D. degree in Material science/nanophysics from Joseph Fourier University based upon the work on “Semiconductor Quantum Dots for Opto-chemical Sensor Application” at French Alternative Energies and Atomic Energy Commission (CEA), France. Her postdoctoral experiences include working as a research scientist at the California Nano Systems Institute and Electric Engineering Department, University of California, Los Angeles (UCLA), USA, and as an experienced researcher at the Nanowiring-Marie Curie Initial Training Network, Georg August Universität Göttingen, Germany. Currently, she is working as an Assistant Professor at Prince Mohammad Bin Fahd University, Saudi Arabia.