Cilia: Development and Disease, 1st Edition (Hardback) book cover


Development and Disease, 1st Edition

Edited by Paraskevi Goggolidou

CRC Press

240 pages | 16 Color Illus.

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Hardback: 9781498703680
pub: 2018-02-28
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The scope of the book is to highlight the diverse roles of cilia in human development and disease. Almost all cell types form cilia and although they were first detected about 200 years ago, their significance was unclear. In the past ten years, it has become obvious that cilia have got sensory functions, as well as roles in motility and their mis-formation or the deregulation of the signaling pathways they control has been associated with defective development and human disease. Although research has concentrated on the role of the cilium in each organ, no effort has been made so far to bring all this information together and relate it to the various human diseases. This book aims to gather all the expertise that has been acquired on primary cilia and translate it into a medical and research context that will be of interest to postgraduate students, researchers, medics and scientists.

Table of Contents

Cilia in the Brain – Development and Disease

Gilbert Lauter, Peter Swoboda and Isabel Tapia-Páez

Cilia in Lung Development and Disease

Laura L. Yates, Hannah M. Mitchison and Charlotte H. Dean

The Role of Cilia in Heart Development and Disease

Sigolène M. Meilhac

Cilia in Kidney Development and Disease

Paraskevi Goggolidou

The Role of Cilia in Pancreatic Development and Disease

Jantje M. Gerdes

The Role of Cilia in Skeletal Development and Disease

Miriam Schmidts

The Role of Cilia in Development and Disease of the Eye

S. Patnaik, V. Kretschmer and H. May-Simera

The Role of Cilia in the Auditory System

Helen May-Simera

About the Editor

Paraskevi Goggolidou received her DPhil in Clinical Medical Sciences from the University of Oxford and her BSc in Molecular Genetics from King's College London. She is currently employed by The Open University and University College London. Dr. Goggolidou has contributed to ten publications.

Subject Categories

BISAC Subject Codes/Headings:
SCIENCE / Life Sciences / Cytology
SCIENCE / Life Sciences / Genetics & Genomics
SCIENCE / Life Sciences / Biology / Developmental Biology
SCIENCE / Life Sciences / General