Clinical Disorders and Experimental Models of Erythropoietic Failure: 1st Edition (Hardback) book cover

Clinical Disorders and Experimental Models of Erythropoietic Failure

1st Edition

Edited by Melvin H. Freedman, Stephen A. Feig

CRC Press

182 pages

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Hardback: 9780367235253
pub: 2019-05-23
eBook (VitalSource) : 9780429280177
pub: 2019-06-04
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First published in 1993: This is the only recent book available that is completely devoted to failures of red blood cell production. A comprehensive review of the physiology of normal and deficient erythropoiesis is presented in a developmental perspective. The chapters provide the most up-to-date clinical concepts and trials, pose the important physiologic questions yet to be answered, and comprehensively review relevant modern technology in the assessment of erythroid failure.

A pathophysiologic exposé gives students and others a simplified understanding of the subject. The book provides the clinician with a recommended approach to differential diagnosis, prognosis, and practical therapy for patients with aregenerative anemia. The relevance of biology is stressed by the analysis of animal models of anemia that have enhanced the understanding of erythropoietic failure in man.

Table of Contents

1. Embryonic and Fetal Erythropoiesis

D. Wade Clapp and Kevin M. Shannon

2. Diamond-Blackfan Anemia

Jeffrey M. Lipton and Blanche P. Alter

3. Transient Erythroblastopenia of Childhood

Bertil E. Glader

4. Pure Red Cell Aplastia: Biology and Treatment

Sanford B. Krantz

5. Miscellaneous Forms of Acquired Red Cell Aplasia and Erythropoietic Failure in Childhood

Melvin H. Freedman and Stephen A. Feig

6. An Animal Model of Pure Red Cell Aplasia

Janis L. Abkowitz

7. The White Spotting and Steel Hereditary Anemias of the Mouse

Richard Blowin and Alan Bernstein

About the Authors/Editors

Stephen A Feig, M.D., is Professor of Pediatrics at the UCLA school of Medicine and Chief, Division of Pediatric Hematology/Oncology at the UCLA Medical Center, Los Angeles, California.

Melvin H. Freedman, M.D. F.R.C.P.C., is chief of Hematology, Hospital for Sick Children and Professor of Pediatrics, University of Toronto Faculty of Medicine, Toronto, Canada.

About the Series

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / General
MEDICAL / Hematology