First published in 1993: This is the only recent book available that is completely devoted to failures of red blood cell production. A comprehensive review of the physiology of normal and deficient erythropoiesis is presented in a developmental perspective. The chapters provide the most up-to-date clinical concepts and trials, pose the important physiologic questions yet to be answered, and comprehensively review relevant modern technology in the assessment of erythroid failure.
A pathophysiologic exposé gives students and others a simplified understanding of the subject. The book provides the clinician with a recommended approach to differential diagnosis, prognosis, and practical therapy for patients with aregenerative anemia. The relevance of biology is stressed by the analysis of animal models of anemia that have enhanced the understanding of erythropoietic failure in man.
1. Embryonic and Fetal Erythropoiesis
D. Wade Clapp and Kevin M. Shannon
2. Diamond-Blackfan Anemia
Jeffrey M. Lipton and Blanche P. Alter
3. Transient Erythroblastopenia of Childhood
Bertil E. Glader
4. Pure Red Cell Aplastia: Biology and Treatment
Sanford B. Krantz
5. Miscellaneous Forms of Acquired Red Cell Aplasia and Erythropoietic Failure in Childhood
Melvin H. Freedman and Stephen A. Feig
6. An Animal Model of Pure Red Cell Aplasia
Janis L. Abkowitz
7. The White Spotting and Steel Hereditary Anemias of the Mouse
Richard Blowin and Alan Bernstein
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