First published in 1990, this timely book provides the first comprehensive state-of-the-art updates on various aspects of sperm motility. The first section describes in detail the structures, molecules and regulatory mechanisms involved in sperm movement. Also reported are the effects of external milieu and egg factors on the initiation and types of sperm motility. The second section covers how to measure sperm motility in human semen and in capacitating media. The book addresses the prognostic value of motility parameters in cases of infertility. It covers the clinical significance of various drugs and toxins on sperm motility and the clinical management of infertile males with sperm motility defects. This volume is indispensable to biochemists, cell biologists and andrologists interested in cell motility, and to urologists, obstetricians, gynecologists, and endocrinologists involved in the management of infertility. It is of value to those in reproduction, animal science, veterinary science, and vertebrate zoology. The book contains basic and clinically relevant information for graduate students, researchers and clinicians.
Table of Contents
PART I. Mammalian Spermatozoa: Structure and Assembly of the Tail. Beating Patterns of Mammalian Spermatozoa. Genetic Analysis of Sperm Motility. A New Theory on the Acquisition of Sperm Motility During Epididymal Transit. Interaction Between the Female Reproductive Tract and Spermatozoa. Capacitation, the Acrosome Reaction, and Motility in Mammalian Sperm. Mode of Action of Egg Peptides. Sperm Chemotaxis. Acquisition and Initiation of Sperm Motility. The Energetics of Fish Sperm Motility. The Bioenergetics of Mammalian Sperm Motility. Structural and Biochemical Activities of the Dynein ATPase. Protein-Carboxyl Methylation and Sperm Motility. Role of cAMP, Calcium and Protein Phosphorylation in Sperm Motility. Protease Involvement in Sperm Motility. Computerized Quantitation of Flagellar Motion in Mammalian Sperm. PART II. Semen Analysis and Sperm Washing Techniques. Motility Parameters and Fertility. Hyperactivated Motility of Human Spermatozoa During in vitro Capacitation and Implications for Fertility. Influence of Seminal Plasma Components on Sperm Motility. Clinical Management of Men with Disorders of Sperm Motility. The Effects of Pharmaceutical, Environmental and Occupational Agents on Sperm Motility. Index.