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Cyclization Reactions provides a quick update of the latest advances in cyclization reactions. It covers the basic principles of cyclization chemistry, emphasizing practical applications. Chapters are organized according to the different cyclization intermediates-cationic, radical, anionic, and metal complex intermediates. The last chapter covers macrolactonization, vicinal tricarbonal, and Bergman (enediyne) reactions, which are of particular interest today.
More than 2,600 structures illustrate key concepts throughout the book. Various cyclizations are organized into mechanistic groups to help researchers choose and change between methods when searching for maximum efficiency in synthesis. Critical coverage of the literature up to 1992 is provided.
Cyclization Reactions is essential reading for anyone involved in the synthesis of ring compounds or who is seeking a rapid overview of the field. Newcomers as well as experienced researchers will benefit from this book. It also is excellent reference material for students at the advanced undergraduate and graduate levels.