Dendrimers Nanomedicine : Concept, Theory and Regulatory Perspectives book cover
1st Edition

Dendrimers Nanomedicine
Concept, Theory and Regulatory Perspectives

  • Available for pre-order. Item will ship after January 26, 2021
ISBN 9780367466053
January 26, 2021 Forthcoming by CRC Press
320 Pages 20 Color & 70 B/W Illustrations

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Book Description

Nanomaterials and nanotechnology are extensively being developed, designed, engineered, tailored, manipulated, explored and investigated for variety of applications in Healthcare, Pharmaceutical, and Biotechnological Research and Innovation area. Nanotechnology based products are rapidly growing and multifunctional engineered nanomaterials (ENM) are emerging as useful tools in biotherapeutics delivery as well.

Among various nanomaterials, dendrimers have attracted great attention of scientists and have proved their usefulness and applications in Healthcare, Pharmaceutical, and Biotechnological Research attributed to their unique properties like monodispersity, hyperbranched structure synthesized by controlled chemical reactions, nanometric size and shape.

Salient Features:

  1. Covers dendrimer advance and future opportunity in nanomedicine with safety and efficacy in development of products
  2. Presents overview of recent progress in the field, its advances and bottlenecks, will help researchers to get a general insight of dendrimers applications
  3. Provides comprehensive overview of latest research efforts in designing, optimizing, development, scale up of dendrimers mediated delivery systems

The proposed book is edited by two well-known researchers in the area of nanomaterials, including dendrimers, carbon nanotubes, quantum dots etc, based drug delivery applications and contribution of vivid chapters from renowned formulator, researcher and academician across the world with their specialization area of interest in the field of chemistry, biology, pharmacy and nanomedicine. 

Table of Contents

Nanotechnology: Introduction and Basic Concepts
Brijesh Ojha, Vineet Kumar Jain, Neelesh Kumar Mehra, Keerti Jain

Fundamental aspects of Targeted Drug Delivery
Javed Ahmed Ameeduzzafar, Nabil K Alruwaili, Syed Sarim Imam, Muhammad Afzal, Khalid Saad Alharbi, Md. Rizwanullah, Javed Ahmad

Dendrimers Nanomedicine: History, concept and properties of dendrimers
Smriti Sharma

Classification and Type of dendrimers, Introduction and Chemistry
Anjali Rajora, Kalpana Nagpal

Macromolecular architecture and Molecular modelling of dendrimers
Rahul Gauro,Keerti Jain, Vineet Kumar Jain, Neelesh Kumar Mehra, Harvinder Popli

Synthesis of the Dendrimers
Abha Sharma, Ashima Thakur

Functionalization of the Dendrimers
Divya Bharti Rai, Deep Pooja, Hitesh Kulhari

Characterization of dendrimers: methods and tools
Sreejan Manna, Sougata Jana

Dendrimers-ghost interaction chemistry
Valamla Bhavana, Neelesh Kumar Mehra and Keerti Jain

Dendrimers in gene delivery
Dnyaneshwar Baswar, Ankita Devi, Awanish Mishra

Dendrimers in Diagnostics Application
Biplab Sikdar, Gagandeep Maan, Sri Madhuri S, Awanish Mishra

Dendrimers-nanomaterials conjugation: Concept, chemistry and application
Sonali Batra, Samridhi Thakral, Amit Singh and Sumit Sharma

Smart functionalized dendrimeric medicine in cancer therapy
Vijay Mishra, Manvendra Singh, Pallavi Nayak

Drug Delivery potential of Dendrimeric formulation
Musarrat Husain Warsi, Abdul Muheem, Abuzer Ali, Mohammad Yusuf, Mohammad Akhlaquer Rahan, Saima Amin, Javed Ahmad

Biomedical applications of Dendrimers
Sonali Batra and Sumit Sharma

Biofate, toxicity and regulatory consideration of dendrimers
Anisha D’Souza and Pratik Kumar Patel

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Dr. Neelesh Kumar Mehra is working as Assistant Professor of Pharmaceutics, at Department of Pharmaceutics, National Institute of Pharmaceutical Education & Research (NIPER), Hyderabad, India. He earned his PhD with Prof. N.K. Jain from Dr. H.S. Gour University, Sagar and PostDoc from Texas A & M Health Science Centre, Kingsville, TX, USA. He served as Manager in Product Development, Sentiss Pharma Pvt Ltd. Gurgaon for development, scale-up and technology transfer of complex ophthalmic, inhalation, and otic pharmaceutical products. He received "TEAM AWARD" for successfully commercialization of Ophthalmic Suspension product. He is as an Editorial member of "Drug Delivery Letters" Journal, Bentham sciences. He has authored more than 50 peer-reviewed publications in high repute International Journals, 07 book chapters contributions. He guided PhD and M.S. students for their dissertations/research projects. He has received numerous outstanding awards including Young Scientist, Team Awards for their research output. He is peer reviewer of various international Journals and publishers. Currently he is editing books on Biopharmaceutical and nanotechnology based with CRC Press and Elsevier Pvt Ltd. He has 11 years rich research and teaching experience in the formulation and development of complex, innovative ophthalmic and injectable biopharmaceutical products including micro- and nano-technologies for regulated market and so on.

Dr. Keerti Jain earned her M. Pharm. and doctorate degree from Dr. H. S. Gour Central University, Sagar. She did her Post Doctorate from M. S. University of Vadodara, India as SERB-National Post-Doctoral Fellow. She has more 10 years of research experienced on Nanomedicine based drug delivery systems. Currently, she is efficiently fulfilling her responsibilities as Asst. Prof. and Scientists at Department of Pharmaceutics, NIPER, Rae Bareli, Lucknow, UP INDIA. Dr. Jain has supervised M. Pharm. and Pharm. D. students for their research works which have been published in quality journals with good impact factor. She is author of more than 60 international manuscripts in peer reviewed-high impact journals, including publications in Progress in Polymer Science having impact factor: 26.932, in biomaterials, drug discovery today, nanomedicine Current Opinion in Pharmacology, Antimicrobial agents and chemotherapy and other high impact factors. Her review articles entitled "Dendrimer Toxicity: Let’s Meet the Challenge" and "Dendrimers as Nanocarriers in Drug Delivery" published in International Journal of Pharmaceutics (2010) and Progress in Polymer Science (2014) was listed in top 25 articles. She has been author of 10 books and book chapters with international publishers. She has been awarded with research fellowships including SERB – Post Doctorate Fellowship, Senior research fellowship (CSIR), Junior research fellowship (UGC), Fellowship for training of young scientist (MPCST), Travel grant award (INSA) and International Travel Fellowship (ICMR and DBT) apart from several other prestigious grants, fellowships and awards. She has been nominated for Ranbaxy Research Scholar Award – 2012 and BioAsia Innovation Award – 2015. She has also been awarded with many best research presentation award in international conferences like NIPiCON-2014, International Science Congress-2012, APTI – Jaipur – 2018, SPER-Bangkok – 2019 and so on. She has been recipient of Pharmaceutical Science Alumni Award-2006 at Dr. H. S. Gour University, Sagar (M.P.). Till date she has been invited to present her research work at several national and seven international conferences including ICYRAM-2012 held at Singapore, Bioencapsulation – 2016 held at Lisbon, Portugal and International Conference – 2019 held at Bangkok. She won most innovative Idea award in LUFTHANSA impact week, which is a Reputed international platform.