This valuable new book offers a new perspective on dendrimers that bridges the gap between basic research and applied nanomedicine. It explores the ultimate effectiveness of dendrimers in theranostics, a promising field that combines therapeutics and diagnostics into single multifunctional formulations used to affect therapy or treatment of a disease state. The authors examine the potential uses of dendrimers, which have proven their capabilities in local/systemic drug delivery, physical stabilization of the drug, solubility enhancement of the poorly soluble drugs, and gene delivery.
Table of Contents
Introduction: Nanotechnology and Medical Science. The Concept of Dendrimers. Synthesis and Types of Dendrimers. Molecular Modeling Techniques to Study Dendrimers. Dendrimer-Drug Interactions. Dendrimers and Drug Delivery. Dendrimers and Gene Delivery. Dendrimers in Diagnostics. Miscellaneous Biomedical Applications of Dendrimers. Toxicity of Dendrimers. Emerging Aspects in Dendrimer Research.
"Among various recent books on dendrimers, this one focuses on the very promising, but still challenging, field of nanomedicine/personalized medicine. It is not exhaustive, as the field is already very broad, but, besides classical topics such as drug and gene delivery and diagnosis, it deals also with topics rarely discussed previously, such as molecular modeling, toxicity studies, and it addresses also emerging areas. An inspiring book for the dendrimers community, in chemistry, biology, and nanomedicine!"
Anne-Marie Caminade, CNRS, Laboratoire de Chimie de Coordination, Toulouse, France; and University of Toulouse, France