First published in 1988, developments in cancer chemotherapy offers a well-rounded guide into the many facets and factors regarding chemotherapy as a method of treatment. Split into 9 chapters, this volume explores the nature of cancer cells and their development, regulation of cancer cells, and using the appropriate therapy tailored to the patient’s needs.
1. Cellular Oncogenes as Biotherapeutic Targets for the Differention and Inhibition of Cancer Cells. 2. Inhibition of Growth Factor Action as an Approach to Cancer Chemotherapy. 3. Disruption of Cellular Growth Control and Signal Transduction Mechanisms as a Target for Cancer Chemotherapy. 4. Regulators of Signal Transduction: Families of GTP-Binding Proteins. 5. Site-Selective cAMP Analogs in the Arrest of the Cancer Cell Growth. 6. N-Myristoylation as a Novel Molecular Target for the Design of Chemotherapeutic Drugs. 7. Mechanisms of Resistance to Antineoplastic Drugs. 8. RNA as a Target for Antimetabolites. 9. Topoisomerase II Inhibition by Antitumor Intercalators and Demethylepipodophyllotoxins.
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