Drug Abuse Handbook  book cover
2nd Edition

Drug Abuse Handbook

ISBN 9780849316906
Published December 21, 2006 by CRC Press
1285 Pages 169 B/W Illustrations

FREE Standard Shipping
USD $280.00

Prices & shipping based on shipping country


Book Description

Following the well-received first edition, the Drug Abuse Handbook, Second Edition is a thorough compendium of the knowledge of the pharmacological, medical, and legal aspects of drugs. The book examines criminalistics, pathology, pharmacokinetics, neurochemistry, treatment, as well as drugs and drug testing in the workplace and in sports, and the ethical, legal, and practical issues involved.

Dr. Karch gathers contributions from 80 leading experts in their respective fields to update and revise this second edition with more than 40 percent new material. New topics include genetic testing in drug death investigation, the neurochemistry of nicotine and designer amphetamines, genetic doping in sports, and the implications of the Daubert ruling on the admissibility of scientific evidence in federal court.

Packed with the latest information in an easily accessible format, the book includes tables of all Scheduled Drugs, methods of Drug Quantitative Analysis, and a glossary of forensic toxicology terms. Vivid pictures and diagrams illustrate the pathological effects of drugs and the chemical make-up and breakdown of abused drugs. It includes more than 6000 references to the best sources in medicine, pharmacology, and the law.

This book addresses specific problems in drug testing, drug-related medical emergencies, and the physical, neurochemical, and sociological phenomenon of addiction. With unparalleled detail and the highest level of authoritative information, The Drug Abuse Handbook, Second Edition is the definitive resource for drug related issues.

Table of Contents

Criminalistics: Introduction to Controlled Substances, J. P. Bono
Definition and Scheduling of Controlled Substances
Scheduling of Controlled Substances
Controlled Substance Analogue Enforcement Act of 1986
Controlled Substances
Legitimate Pharmaceutical Preparations
Unique Identify Factors
Analyzing Drugs in the Forensic Science Laboratory
Comparative Analysis
Clandestine Laboratories

Pathology of Drug Abuse, Edited by C. V. Wetli
The Scene of Death and the Autopsy
Heart Disease
Myocardial Alterations in Drug Abusers, S. B. Karch
Valvular Heart Disease, M. D. Bell
Lung Disease, M. D. Bell
Disorders of the Central Nervous System, M. Bell

Pharmacokinetics: Drug Absorption, Distribution, and Elimination, A. J. Jenkins
Basic Concepts and Models
Pharmacokinetic Modeling
Pharmacokinetic-Pharmacodynamic Correlations
Factors Affecting Pharmacokinetic Parameters
Pharmacokinetics of Specific Drugs

Pharmacodynamics, Edited by S. J. Heishman
Effects of Abused Drugs on Human Performance: Laboratory Assessment, S. J. Heishman and C. S. Myers
Performance-Based Assessment of Behavioral Impairment in Occupational Settings, T. H. Kelly, R. C. Taylor, S. J. Heishman, and J. Howland
Effects of Pupillometry and Eye Tracking as Predictive Measures of Drug Abuse, W.B. Pickworth and Rudy Murillo
Abuse of Marketed Medications, K. L. Preston, D. H. Epstein, J. P. Schmittner, and S. L. Walsh

Measuring Acute Alcohol Impairment
Update on Clinical and Forensic Aspects of Alcohol, A. W. Jones and D. J. Pounder
Post-Mortem Alcohol - Aspects on Interpretation, D. J. Pounder and A. W. Jones
Recent Advances in Biochemical Tests for Acute and Chronic Alcohol Consumption, A. Helander and A. W. Jones

Neurochemistry of Drug Abuse, Edited by J. K. Staley and K. P. Cosgrove
The Dopamine Transporter and Addiction, W. M. Meil1 and J. W. Boja
Neurochemistry of Nicotine Dependence, D. H. Brunzell
Neurochemical Substrates of Habitual Tobacco Smoking, I. Esterilis, S. Krishnan-Sarin, and J. K Staley
Neurochemical and Neurobehavioral Consequences of Methamphetamine Abuse, C. N. Haile.
Neurochemical Adaptations and Cocaine Dependence, K. P. Cosgrove and J. K. Staley
Neuropsychiatric Consequences of Chronic Cocaine Abuse, D. C. Mash
Neurobiology of 3,4-Methylenedioxymethamphetamine (MDMA, or "Ecstasy"), M. H. Baumann and R. B. Rothman

Addiction Medicine, Edited by K. Wolff
The Principles of Addiction Medicine, D. Raistrick
Substitute Prescribing, K. Wolff
Treatment of Withdrawal Syndromes, J. Banbery
Replacement Prescribing, K. Wolff
Management of Comorbidity
Toxicologic Issues

Medical Complications of Drug Abuse, N. L. Benowitz
Medical Aspects of Drug Abuse, S. Zevin and N. L. Benowitz
Emergency Management of Drug Abuse, B. A. Roth, N. L. Benowitz, and K. R. Olson

Sports, Edited by M. D. Bollmann and M. Saugy
Testosterone and Synthetic Anabolic Steroids, C. Saudan and N. Baume
Stimulants, L. Avois-Mateus
Erythropoietin - Blood Doping, N. Robinson
Human Growth Hormone, M. Saugy
Cannabinoids, C. Giroud
Ethanol Use in Sport and Interaction with Other Doping Agents
Morbidity of Doping, M. D. Bollmann and P. Mangin
Mortality of Doping - Sudden Death in Athletes, M. D. Bollmann
The Future of Doping: New Drugs and Genetic Doping, C. Giroud and M. D. Bollmann

Workplace Testing, Edited by Y. H. Caplan and M. A. Huestis
Drugs in the Workplace, Y. H. Caplan and M. A. Huestis
Federal Regulation of Workplace Drug and Alcohol Testing
Workplace Drug Testing outside the U.S., A. Pierce
Analytical Considerations and Approaches for Drugs, D. Isenschmid and B. A. Goldberger
Analytical Approaches for Drugs in Biological Matrices Other Than Urine, P. Kintz, M. Villain, and V. Cirimele
Interpreting Alternative Matrix Test Results, E. J. Cone, A. Sampson-Cone, and M. A. Huestis
Specimen Validity Testing, Y. H. Caplan
The Role of the Medical Review Officer in Workplace Drug Testing, J. A. Thomasino
Quality Practices in Workplace Testing, J. M. Mitchell and F. M. Esposito
Current Legal Issues of Workplace Drug Testing, T. F. Shults

Point of Collection Drug Testing
Point of Collection Testing of Alternative Specimens (Other Than Urine), A. Verstraete and J. M. Walsh
Point of Collection Testing in Criminal Justice, L. Kadehjian
Regulatory Concerns for Point of Collection Testing in the Workplace, M. R. Baylor, C. A. Sutheimer, and S. D. Crumpton
Determination of Alcohol in Point of Collection Testing, J. R. Zettl
On-Site Point-of-Collection Drug Testing: History, Development, and Applications, J. Tsai

Post-Mortem Toxicology, Edited by H. Druid
Introduction to Postmortem Toxicology, W. L. Hearn and H. C. Walls
Specimen Selection, Collection, Preservation, and Security, B. R. Hepler and D. S. Isenschmid
Common Methods in Post-Mortem Toxicology, W. L. Hearn and H. C. Walls
Strategies for Post-Mortem Toxicology Investigation, Edited and Revised by H. Druid, from the original by W. L. Hearn
Quality Assurance in Post-Mortem Toxicology, W. Andollo
Interpretation of Post-Mortem Drug Levels, G. R. Jones

Pharmacogenomics for Toxicology, R. M. White, Sr. and S. H. Y. Wong
Heritable Channelopathies and Myopathies, K. A. Glatter, J. Calkins, and S. J. Ayirookuzhi

Drug Law
DUI Defenses, A. W. Jones and B. K. Logan
Testing Claims of Adverse Drug Effects in the Courtroom, J. G. Hollingsworth and E.G. Lasker

Appendix Ia: Glossary of Terms in Forensic Toxicology, Compiled by C. Walls
Appendix Ib: Common Abbreviations, Compiled by C. Walls
Appendix Ic: References for Methods of Drug Quantitative Analysis
Appendix II: Sample Calculations, B. K. Logan and A. W. Jones
Appendix III: Predicted Normal Heart Weight (g) as a Function of Body Height in 392 Women and 373 Men

View More


"…Virtually no stone is left unturned. This is the most comprehensive volume I have ever had the pleasure of reading."
- Joseph Horvat, Weber State University, Ogden, Utah, in Science Books and Films

". . . extensive and comprehensive text . . . This is a reference work but also a very useful volume for academics, scientists, lawyers and medical practitioners who wish a very good starting point for a wide range of issues and topics relevant to drug abuse."

– James Robertson, National Manager, Forensic and Technical Australian Federal Police, September 2008