The most highly acclaimed pharmacology and toxicology text/reference used in Europe is now available in English. This excellent translation of Mutschler's Arzneimittelwirkungen combines a clear, informative narrative with 255 figures, 261 diagrams, and 198 tables to appeal to both new students and experts in pharmacy, pharmacology, and therapeutics. Drug structure and activity relationships are emphasized as an important dimension that is sometimes lacking in other pharmacology texts.
Drug Actions is organized into three major sections covering general drug action and dosing principles, specific drug therapeutics, and toxicology. The first section provides an integrated overview of basic principles in pharmacology with chapters addressing pharmacokinetics, pharmacodynamics, drug side effects, drug interactions, chronopharmacology, rational and irrational drug combinations as well as drug developments and drug trials. The second section systematically describes specific drug actions with pharmacology, clinical indications, standard doses side effects, and contraindications described for each approved drug category. The third section addresses toxicology where specific drug toxicities are identified and treatment options for accidental and drug associated poisoning are presented. Topics covered include environmental, occupational, and nutritional exposure to toxins.
General Pharmacology: Definitions. Pharmacokinetics. Pharmacodynamics. Pharmacogenetics. Side Effects (Undesired Side Effects). Drug Interactions. Chronopharmacology. Fixed Drug Combinations. Drug Development and Drug Trials. Specific Pharmacology: Nervous System. Hormonal System. Cardiovascular System. Respiratory Tract. Gastrointestinal Tract. Kidney and Urinary System, Water and Electrolyte Regulation. Skin. Vitamins. Infectious Diseases. Chemotherapy of Malignant Tumors. Toxicology: General Toxicology. Emergency Management of Poisoning. Specific Poisonings. Table of Toxic Compounds.