Drug Delivery and Development of Anti-HIV Microbicides: 1st Edition (e-Book) book cover

Drug Delivery and Development of Anti-HIV Microbicides

1st Edition

Edited by Jose das Neves, Bruno Sarmento

Pan Stanford

706 pages

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Hardback: 9789814463560
pub: 2014-10-16
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pub: 2014-10-16
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Description

The worldwide impact of HIV/AIDS is well recognized. This book provides for the first time a thorough and critical overview of current aspects, recent developments, and trends in the formulation and drug delivery concerning anti-HIV microbicides by leading scientists in the field. Additionally, pertinent regulatory aspects and socioeconomical issue

Table of Contents

Preface. Microbicides and the HIV Pandemic. HIV Transmission Models: Lessons Learned for Microbicide Formulation Design. Challenges in Microbicide Drug Delivery: Identifying Targets and Evolving Strategies. Safety Issues Related with Microbicide Formulations. Biophysics, Drug Transport Modeling and Performance of Microbicide Formulations. Dosage Forms for Microbicides Formulation: Advantages and Pitfalls. Microbicide Vaginal Rings. Vaginal Microbicide Films. Rectal Microbicide Development, Formulation and Delivery. Design of Stimuli-Sensitive Microbicide Formulations. Nanotechnology-Based Systems for Microbicide Development; Nanofibers for Microbicide Drug Delivery. Modified Microflora for Microbicide Drug Delivery. Scale-up, Affordability and Intellectual Property Issues Related with Microbicide Formulation Development. Regulatory Issues Pertaining Microbicide Products.Socioeconomic and Behavioral Factors Influencing Choice, Adherence and Success of Microbicide Formulations.

About the Editors

Jose das Neves has a PhD in pharmaceutical sciences from the University of Porto, Portugal. He is a researcher at Instituto Superior de Ciencias da Saude-Norte, CESPU, Gandra, Portugal and Faculty of Pharmacy, University of Porto, Portugal. His current research interests include vaginal drug delivery and the development of nanotechnology-based solutions for the development of anti-HIV microbicides.

Bruno Sarmento has a PhD in pharmaceutical technology from the University of Porto, Portugal. He is an affiliated researcher at INEB - Instituto de Engenharia Biomedica, University of Porto, Portugal and assistant professor of pharmaceutical and biopharmaceutical technology at Instituto Superior de Ciencias da Saude-Norte, CESPU, Gandra, Portugal. His current research focuses on nanomedicines and their application in the pharmaceutical and biomedical fields.

Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
MED022090
MEDICAL / Infectious Diseases
MED071000
MEDICAL / Pharmacology