This book is comprised of reviews on the chemotherapy of mycobacterial infections, as well as descriptions of established methods and new techniques for drug susceptibility testing. Some of the fascinating topics examined include the activity of conventional and experimental antimicrobial agents, the rationale of drug combinations in chemotherapy, pharmacokinetics, and the problems of drug susceptibility of mycobacteria analyzed using standards established in other fields of clinical microbiology. Any physician or researcher involved with the therapy of tuberculosis, leprosy, M. avium in AIDS patients and other mycobacterial infections, and drug susceptibility testing will discover a wealth of information in this comprehensive volume.
Preface. INTRODUCTION: DRUG SUSCEPTIBILITY TESTS AND THE CLINICAL OUTCOME OF CHEMOTHERAPY ANTITUBERCULOSIS DRUGS: ANTIMICROBIAL ACTIVITY IN VITROANTITUBERCULOSIS DRUGS: PHARMACOKINETICS DRUG SUSCEPTIBILITY TESTS IN THE MANAGEMENT OF CHEMOTHERAPY OF TUBERCULOSIS DILEMMAS AND REALITIES IN DRUG SUSCEPTIBILITY TESTING OF MYCOBACTERIUM AVIUM-M. INTRACELLULARE AND OTHER SLOWLY GROWING NONTUBERCULOUS MYCOBACTERIA DRUG SUSCEPTIBILITY TESTS FOR Mycobacterium FORTUITUM AND Mycobacterium CHELONAE DETECTION OF RESISTANCE IN MYCOBACTERIUM LEPRAE AND THE DESIGN OF TREATMENT REGIMENS FOR LEPROSYDRUG COMBINATIONS