Early Breast Cancer: From Screening to Multidisciplinary Management, Third Edition, 3rd Edition (Hardback) book cover

Early Breast Cancer

From Screening to Multidisciplinary Management, Third Edition, 3rd Edition

Edited by John R Benson, Gerald P.H. Gui, Todd Tuttle

CRC Press

584 pages

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Hardback: 9781841848853
pub: 2013-01-03
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pub: 2013-01-03
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First Prize, BMA Medical Book Awards 2013

Breast cancers are now detected earlier and are thus more likely to be confined to the breast itself and regional nodes. Many of these tumours will have minimal proclivity for hematogenous dissemination and formation of micrometastases. On the other hand, some patients have micrometastatic diseases which can remain dormant and be activated many years after initial diagnosis.

Early Breast Cancer: From Screening to Multidisciplinary Managementdiscusses the principles and practice of breast cancer management with respect to both screen-detected and symptomatic disease. It provides readers with sound understanding and critical insight into many aspects of the disease from epidemiology, genetics, and screening to pathology, diagnosis, treatment, and prevention. This latest edition continues the general ethos of the second edition with an emphasis on early screening and continued development of the multidisciplinary team.


Praise for the Previous Editions

"Early breast cancer calls for a specially designed multidisciplinary approach to management, challenging radiologists, surgeons, pathologists, and oncologists to adopt new concepts and strategies. To this end, all the specialized fields involved will benefit from the most comprehensive knowledge currently available on the subject. Early Breast Cancer conveys the relevant data without losing sight of clinical relevance. The information in this book shows how a growing number of patients can profit from timely diagnosis and treatment and substantially increase their chances of surviving breast cancer."

New England Journal of Medicine, September 1999

"The book demands space on many bookshelves, because it is possibly the best reference book to date on the subjects it covers."

New England Journal of Medicine, June 2006

Table of Contents


An Introduction to Screening for Breast Cancer, Linda J. Pointon, Sue K. Down

Mammographic Density as an Early Indicator of Breast Cancer, Jajini Susan Varghese

Genetic Predisposition and Breast Screening, D. Gareth Evans

Application of New Genomic Technologies to Breast Cancer Risk Assessment, Mark Robson

Endocrine Prevention of Breast Cancer, Russell E. McDaniel, V. Craig Jordan


The Biological Basis for Breast Cancer Screening and Its Relevance to Treatment, John R. Benson

Interval Cancers, Anthony J. Maxwell

Survival Advantage of Screen-Detected Cancer over Stage-Matched Symptomatic Cancer, Gordon C. Wishart

Mammography Screening for Women under Age 50, Ismail Jatoi, Pranjali V. Gadgil

Mammographic Screening in Women Aged 50 Years and Above, Chris I. Flowers

The Organization of Breast Screening, Julietta Patnick

Quality Assurance and Evaluation of Outcomes in the NHS Breast Screening Programme, Gill Lawrence


Clinical Assessment of Symptomatic Patients, J. Mathew, K.L. Cheung

Film Reading and Recall from Screening Mammography, Sabrina Rajan, Susan J. Barter, Erika Denton

Radiology of the Normal Breast and Differential Diagnosis of Benign Breast Lesions, Jessica Kuehn-Hajder, Claudia Engeler, Tim Emory

Breast Masses, A. Robin M. Wilson

Asymmetry and Architectural Distortion, Michael J. Michell

The Radial Scar, Sabrina Rajan, Pauline J. Carder

Role of Ultrasound in the Diagnosis of Breast Cancer, Hannah Gay, Steven D. Allen

The Role of MRI in Preoperative Evaluation and Postoperative Follow-Up of Breast Cancer Patients, Richard J. Bleicher

PET Scanning and Breast Cancer Management, Rebecca Wight, Patrick Borgen


Core Biopsy of Breast Lesions, Kathryn Taylor, Peter D. Britton

Vacuum-Assisted Breast Biopsy, Thomas Conner, William The

Preoperative Localization of Impalpable Breast Lesions, Sabrina Rajan, Erika Denton, Susan J. Barter


The Normal Breast and Benign Breast Lesions, Baljit Singh

Histological Risk Factors, Prognostic Indicators, and Staging, Emad A. Rakha, Sarah Pinder, Ian O. Ellis

Premalignant and Borderline Lesions: Ductal and Lobular Carcinoma In Situ, Clive A. Wells, Evdokia Arkoumani

Invasive Breast Carcinoma, Elena Provenzano

Molecular Investigation of Breast Cancer, Paul M. Wilkerson, J.S. Reis-Filho


The Role of Multidisciplinary Teams in Breast Cancer Management, Cath Taylor, Amanda Shewbridge, Massimiliano Cariati, Anand Purushotham

Shared Decision-Making for Breast Cancer Patients, Catharine F. Clay, Alice O. Andrews, Dale Collins Vidal

The Evolving Role of the Breast Care Nurse in the Management of Patients with Early Breast Cancer, Rebecca Llewellyn-Bennett, Jane Barker, Zoë Ellen Winters

Informed Consent in the Management and Research of Breast Cancer, Hazel Thornton


Ductal Carcinoma In Situ of the Breast, Melvin J. Silverstein, Michael D. Lagios

Principles of Surgical Treatment of Invasive Breast Cancer, Starr Koslow, Rache M. Simmons

The Optimum Resection Margin in Breast Conservation Surgery, Lisa Newman, Jessica Bensenhaver

Skin-Sparing Forms of Mastectomy, Gerald Gui

Locoregional Recurrence of Breast Cancer, John R. Benson, Katy Teo

Management of the Axilla I, John R. Benson, Mattia Intra

Management of the Axilla II, Laura Dominici, Mehra Golshan


Radiation Therapy Following Breast Conserving Surgery or Mastectomy, Ian Kunkler

Partial Breast Irradiation, Charlotte Coles, Mukesh Mukesh, Martin Keisch

Targeted Intraoperative Radiotherapy for Breast Cancer: Not All Cancers in the Breast Will Grow, Jayant S. Vaidya, John R. Benson, Jeffrey S. Tobias


Systemic Hormonal Therapies for Early-Stage Breast Cancer, Stephen R.D. Johnston

Adjuvant Chemotherapy and Biological Therapies for Early-Stage Breast Cancer, Sausan Abouharb, Francisco J. Esteva

Primary Systemic Therapy in Breast Cancer, Lisardo Ugidos, Andreas Makris, Jenny C. Chang


Breast Cancer in the Rlderly, R.C.F. Leonard, G.A. Thomas

Breast Cancer and Pregnancy, Christobel Saunders, Angela Ives

Male Breast Cancer, Maisam Z. Fazel, Vassilis Pitsinis

Trends in the Use of Contralateral Prophylactic Mastectomy, Todd M. Tuttle

The Principles of Breast Reconstructive Surgery, Animesh J.K. Patel, Rosanna C. Ching, John R. Benson, Charles M. Malata


About the Editors

John R. Benson MA DM (Oxon), MD (Cantab), FRCS (Eng), FRCS (Ed), Addenbroke's Hospital, Cambridge, United Kingdom,

Gerald Gui MS, FRCS, FRCS (Ed) Breast Unit, The Royal Marsden, London, United Kingdom

Todd M. Tuttle MD, MPH Masonic Cancer Center, University of Minnesota, Minneapolis, MN, USA

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Gynecology & Obstetrics
MEDICAL / Oncology